ABSTRACT
To study the clinical features of Wegener's in head and neck structures. Method: We reviewed all selected patients with diagnosis of Wegener's granulomatosis according to ACR criteria from two academic hospitals in Mashhad. 12 patients with diagnosis of WG during the past 10 years were studied. M/F ratio was 2/1 and the majority of them were in the fifth decade of life. 75% of our patients had head and neck related complaints and 65% had lower respiratory tract involvement. Recurrent sinusitis in 45%, nose structure involvement in 72%, eye complaints in 27% and ear involvements were found in 45%. We had one case of eye proptosis and 15% nose deformity. Eight patients had biopsy samples, and granulomatos vasculitis with necrosis were found in 25%. Wegener's granulomatosis is a rare systemic vasculitis in our patients. Ulcer with giant crust, sensory neural hearing loss in association with systemic findings such as low grade fever, fatigue and arthralgia