Seroepidemiology of taxoplasma gondii infection in pregnant woman of Hazara

Five hundred and thirty females were screened for toxoplasma gondii antibodies during pregnancy. Their sera were analyzed for toxo-IgG and toxo-IgM antibodies by EIA technique. One hundred and ninety cases [35.8%] were positive for toxo-IgG, 26 cases [4.9%] were positive for toxo 1gM, and 12 cases [2.2%] were positive for both IgG and 1gM. Significant correlation was found between bad obstetrical history and toxo antibodies. There was significant correlation of toxo antibodies and contact with domestic animals. Correlation with other habits includes use of under-cooked meat. The data suggests that toxoplasmosis is not uncommon in our population and most of the cases are asymptomatic. Use of under-cooked meat should be avoided and those having contact with domestic animals must be regularly screened for toxoplasma gondii antibodies

Bio-chemical profile of schizophrenics

Total serum protien levels and clinical features were studied in a randomly selected group of 30 first episode and 30 `chronic schizophrenics. The results were compared with IS normal controls. The most frequent symptoms were somatic passivity [66%] and voice commenting [40%]. Total serum protien level in both first episode and chronic schizophrenics was in normal range and comparable with the controls. Serum albumin was reduced in first episode followed by chronic schizophrenics and controls. First episode schizophrenic patients had significantly increased levels of gamma globulin as compared to chronic schizophrenics [P<0.01] and normal controls [P<0.01]. The results indicate that schizophrenia might have some connection with alteration in serum gamma globulin levels and the possibility that altered gamma globulin level plays a role in schizophrenia, can not be ruled out