ABSTRACT
To isolate the etiological agent of diarrheal outbreak, identification, antibiogram of isolated bacteria. Stool samples from patients and water samples from reservoir of water collected in transport media. Culture and sensitivity test were performed in Microbiology Laboratory of Bolan Medical Complex Hospital Quetta. The isolated strain was confirmed by National Institute of Health Laboratory Islamabad and Agha Khan University hospital laboratory Karachi. The outbreak was controlled by preventive measures. More than five thousand people affected in the outbreak, including all age and both sexes. Twenty three deaths [0.4%] occurred in this outbreak. The stool samples from patients and from 5 water reservoir tanks collected for analysis of etiological agent responsible for the outbreak. The stool and water samples revealed isolation of Vibrio cholerae Inaba, El Tor, which was sensitive to Ampicillin, Ciprofloxacin, Tetracycline, Doxycyline and intermediate to Choloramphenicol and Erythromycin. Resistant to Nalidixic Acid Polymaxin B, and Co-trimaxazole. The Vibrio cholerae Inaba, El Tor was the causative agent of this outbreak and the first outbreak which occurred in Balochistan due to Vibrio cholerae Inaba, El Tor