ABSTRACT
Kidney Disease has been known to be associated with bone abnormal early as 1883.Despite of the emergence of new and more inclusive terms low turnover and high definition still are useful definitions Aluminum toxicity also is threat among these patients The study was started on 30 patients recruited from several hemodialysis. Units in Tabriz. SIX patients left the study and only 24 patients completed their work up [10 female and 4 males] Immunoradionsetric assay was used to measure the bone specific alkaline phosphatase [BAP] and intact parathyroid hormone [I PTH]. Serum Aluminum was studied by atomic absorption In 8 patients [8124, 33%] serum level of iPTH was lower than 150pg/ml, and in 14 patients [14124, 58%] serum BAP levels was lower than 27 U/L, but only in 5 patients [5/24, 20%] the combination of low iPTH [
ABSTRACT
Cytomegalovirus is the most common viral infection after kidney transplantation. Clinical presentations of Cytomegalovirus infection range from asymptomatic infection to organ-specific involvement. Most symptomatic infections manifest as fever and cyto-penia. The gastrointestinal tract is the most common site of tissue-invasive infection, often presenting as diarrhea or gastrointestinal bleeding. Gastrointestinal obstruction, perforation, thrombosis of large gastrointestinal veins, splenic artery thrombosis, and pancreatitis are rare gastrointestinal presentations of Cytomegalovirus infection. Renal-allograft ureteral stricture and skin involvement are other rare presentations of Cytomegalovirus infection. Hemophagocytic syndrome, thrombotic microangiopathy, adrenal insufficiency, and renal allograft artery stenosis are other rare symptoms of cy-tomegalovirus infection
ABSTRACT
There is a limited knowledge about the morphological features of IgA nephropathy [IgAN]in the middle east region. The objective of this study was to evaluate the spectrum of histopathological findings in IgAN patients at our laboratory. At this work, an observational study reported which was conducted on IgAN patients using the Oxford-MEST classification system. In this survey, of 102 patients 71.6% were male. The mean age of the patients was 37.7 +/- 13.6 years. Morphologic variables of MEST classification was as follows; M1: 90.2%, E: 32%, S: 67% also, T in grads I and II were in 30% and 19% respectively, while 51% were in grade zero. A significant difference was observed in segmental glomerulosclerosis [P=0.003] and interstitial fibrosis/tubular atrophy frequency distribution [P=0.045], between males and females. Furthermore, it was found that mesangial hypercellularity was more prevalent in yonger patients. Moreover, there was a significant correlation between serum creatinine and crescents [P<0.001]. There was also significant correlation of serum creatinine with segmental glomerulosclerosis [P<0.001]. Higher prevalence of segmental glomerulosclerosis and interstitial fibrosis/tubular atrophy, as the two of, four variables of Oxford-MEST classification of IgAN in male patients further attests that male gender is a risk factor in this disease. In this study the significant correlation between serum creatinine and crescent was in an agreement with previous studies and suggests for the probable accomodation of extracapillary proliferation as a new variable in MEST system