Cyclosporine in the treatment of a case of fulminant and refractory acute disseminated encephalomyelitis

Acute disseminated encephalomyelitis [ADEM] is a rare, monophasic, demyelinating disease of the CNS which sometimes could be refractory to traditional treatment. We present a case of fulminant ADEM which is treated with combination of corticosteroid, intravenous immunoglobulin and cyclosporine. Immunosuppressive agents such as cyclosporine may be effective especially in fulminant form of the disease