pharmacoepidemiological study of prescription pattern in outpatient clinics in Southwestern Saudi Arabia

A pharmacoepidemiological study of prescription pattern in outpatient clinics in Southwestern Saudi Arabia. A total of 3796 prescriptions from outpatient clinics of Aseer Central Hospital, Abha, Kingdom of Saudi Arabia were screened randomly and systemically over one-year period [April 2000 to April 2001]. The prescriptions were analyzed for the essential elements of the prescription order, and for the number and classes of drugs prescribed, source of prescription and appropriateness of prescription to the diagnosis. The source of prescriptions was not provided in 61.5% of prescriptions. The diagnosis was missing in 15.1% and not readable in 18.9% of prescriptions. Upper respiratory tract infection [URTI] was the most frequent diagnosis and was included in 21.6% of prescriptions. The average number of drugs per prescription was 2.1 +/- 1.05 [Mean +/- SD], with 90.8% of prescriptions containing 3 or fewer drugs. The most frequently prescribed drugs were nonsteroidal anti-inflammatory drugs [NSAIDs], including paracetamol which were included in 51.2% of prescriptions, followed by antibacterial agents [33.2%]. Only 46.4% of prescriptions were appropriate to the diagnosis, while 11.1% were partially appropriate and 5.3% were inappropriate. For the rest [37.2%], it was difficult to evaluate appropriateness due to deficient information. General practitioners and specialists were more likely to prescribe appropriately than emergency room physicians [64.6% and 60.4% versus 35.7%]. None of the prescriptions for antiplatelet and anticoagulant drugs and antihypertensive agents were inappropriate. These results emphasize the need for continuing medical education on rational prescribing, and for periodic monitoring of physicians habits on drug utilization

Prevalence and risk factors for hepatitis C and Hepatitis B viral infections in haemodialysed patients in southern Saudi Arabia

Haemodialysed patients are prone to contract hepatitis and this poses an additional health problem to both patients and dialysis units. This study was undertaken to study the prevalence of and the risk factors for hepatitis B and C infections in 2 dialysis units in southern Saudi Arabia. Serum samples were tested for HbsAg, HCV Ab and HIV Ab from 159 patients receiving maintenance haemodialysis in the two units. There were 83 males and the mean age was 46 years [range 10 - 90]. The prevalence of HCV Ab, HBsAg and HIV Ab were 36.5%, 5.7% and 0.6% respectively. This was not affected by age or gender, but blood transfusion and duration of dialysis were associated with a higher prevalence. Overall, these values are lower than those from the rest of Saudi Arabia probably due to the strict prophylactic measures in our dialysis centres