ABSTRACT
Twelve mongrel adult male dogs with a complete set of permanent dentition were used in this study. They were randomly divided into four groups [I, II, III and IV] based on time of sacrifice at one month, 1.5 months, 3 months and 6 months postsurgically. Under general anaesthesia; maxillary sinus lift operation was done for all animals on both sides, the left side served as a control side where the osseous defect was filled with bioactive glass particles [BG] and the right side was filled with bioactive glass particles mixed with platelet rich plasma [BG mixed with PRP] and served as study one. The bony specimens at the operation sites were taken after sacrifice; fixed, decalcified and processed for paraffin embedded sections. The sections were studied histologically and histochemically. Histologically with Hx. and E. stain the sections revealed faster bone healing in the study side at all age groups as compared with their counterparts of the control side. Also, with trichrome stain; the bone maturation was also more faster. Histochemically; the PAS reaction was mild at 6 months groups of the study side ahead of the control one. Based on the findings, we can conclude that healing of osseous defect after sinus lift procedure is more enhanced, through an accelerated bone formation and maturation, with the use of BG mixed with PRP than with the use of BG alone