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Zahedan Journal of Research in Medical Sciences. 2014; 16 (10): 12-17
in English | IMEMR | ID: emr-169360

ABSTRACT

The aim of this study was the effect of Myrtus communis extract on liver enzymes and blood biochemical factors in diabetic adult male rats. This study has been carried out experimentally and completely random. Seventy adult male Wistar rats were divided in 7 groups including: control which received no treatment, sham who received 2 mL of distilled water, the 1st, 2nd and 3rd experimental groups which received 0.75, 1.5 and 3 mg/kg Myrtus communis leaf extract respectively, the 4th experimental group as the diabetic control group who received streptozotocin [60 mg/kg] and the 5th experimental group as the diabetic treatment group who received 3 mg/kg of extract. This experiment lasted 14 days with prescript orally. After this period, all the rats, were weighted, anesthetized and blood samples were taken from the heart centrifuged and sera were evaluated for the concentration of various factors. In addition liver were removed and sliced. According to the obtained results, the plasma concentration of liver enzyme [alanine aminotransferase, alkaline phosphatase, aspartate aminotransferase], cholesterol and glucose presented a significant decrease at [p

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