ABSTRACT
Antiphospholipid antibody syndrome [APS] is a recently-diagnosed syndrome presenting with arterial and venous thrombosis, recurrent miscarriages and thrombocytopenia in the presence of antiphospholipid antibodies.A 16- year-old man referred due to right sided chest pain, dyspnea and cyanosis of two fingers presented for 2 months. After a complete workup, diagnosis of pulmonary thromboembolism was confirmed through clinical examination, spiral chest CT-scan and lower limb Doppler sonography.He had positive anticardiolipin antibody, lupus anticoagulant, ANA and anti dsDNA. Based on these findings, diagnosis of APS [probably secondary to SLE] was made. Symptoms were improved by anticoagulant, prednisolone and chloroquine therapy. In a conclusion, pulmonary embolism may be the first presentation of APS, especially in young adults.