Systematic Review: the role of pelvic floor muscles dysfunction in constipation

Purpose: Pelvic floor muscle dysfunction is a common cause of constipation. This dysfunction does not respond to current treatments of constipation. Thus, it is important to identify this type of dysfunction and the role of these muscles in constipation. The purpose of the present study was to review the previously published studies concerning the role of pelvic floor muscles dysfunction in constipation and related assessment methods

Methods: Articles were obtained by searching in several databases including, Elsevier, Science Direct, ProQuest, Google scholar, and PubMed. The keywords that were used were 'constipation,' 'functional constipation,' and 'pelvic floor dysfunction.' Inclusion criteria included articles that were published in English from 1980 to 2013. A total of 100 articles were obtained using the mentioned keywords that among them articles about constipation, its definition, types, methods of assessment, and diagnosis were reviewed. Of these articles, 12 articles were related to the assessment procedures and pelvic floor muscle function in constipation

Results: The overall outcome of the studies provided sufficient evidence indicating the role of pelvic floor muscle dysfunction in constipation

Conclusion: Therefore, attention to this cause is effective in recovery process of these patients. There isn't agreement to better assessment method. It seems that manometry is a good way in the medical field and palpation as an acceptable procedure can be used in rehabilitation field

Accuracy of rapid urease test in diagnosing helicobacter pylori infectino in patients using NSAIDs

This study aimed to determine the effect of nonsteroidal anti-inflammatory drugs [NSAIDs] on the results of rapid urease test [RUT]. The study evaluated 210 consecutive patients for the diagnosis of Helicobacter pylori [H. pylori] infection. They were divided into case and control groups based on history of NSAID use[n=70 each]. Two biopsy specimens were collected from antrum and corpus of stomach during endoscopy and sent for rapid urease testing and histopathology. Sensitivity, specificity, and accuracy rate of RUT test were compared against histology. The average age was 55.2 +/- 12.9 and 43.3 +/- 12.1 years in the case and control groups, respectively. Among NSAID users, RUT sensitivity, specificity and accuracy rate were all 100%. The sensitivity, specificity and accuracy rate of RUT in patients without history of NSAID use were 97.37, 98.57 and 98.14%, respectively. The overall sensitivity, specificity and accuracy rate of RUT were 98.57, 99.29, and 99.04%, respectively. Our study shows that sensitivity, specificity and accuracy rate of RUT are not affected by NSAID use. Rapid urease test remains a reliable test for diagnosis of H.pylori in patients on NSAIDs

Gastritis cystica polyposa in an unoperated stomach, treated by endoscopic polypectomy

Gastritis cystic polyposa is a rare and peculiar polypoid lesion arising at a gas-troenterostomy site, and almost always on the gastric side. It is characterized by elongation of the gastric foveolae along with hyperplasia and cystic dilatation of the gastric glands extending into the submucosal layer. Esophagogastroduodenoscopy in a 47-year-old woman without any history of gastric operation revealed a pedunculated polyp approximately 2 cm in diameter, in a background of erythematous gastric folds along the anterior wall of the fundus. Polypectomy was performed, with endoscopic impression of hyperplastic or fundic gland polyp, without any complications. Histopathological findings were consistent within gastritis cystic polyposa[GCP]. A mild Helicobacter pylori colonization in gastric pits was seen. GCP could occur in an unoperated stomach and treated by endoscopic polypectomy. However, removal and histopathologic confirmation of these lesions are necessary