ABSTRACT
Objectives: prefabricated functional appliances have therapeutic effects similar to those of custom-made functional appliances. This study aimed to assess the dentoskeletal effects of Multi P[registered sign] prefabricated functional appliance on Class II Div 1children in late mixed dentition
Methods: this open label trial was conducted on 18 children aged 9-12 years with Cl II Div 1 malocclusion due to mandibular deficiency during a 9-month period. Written informed consent was obtained from the parents. Multi P[registered sign] [RMO, Strasbourg, France] was used by the patients 4 hours/day and overnight [minimum of 8 hours] in conjunction with specific exercises [pressing the teeth in the recorded occlusion, pressing the tongue against the palate and uninostril breathing]. Patients were visited monthly. Study casts and cephalometric radiographs were obtained before and after the treatment. Data were analyzed using paired samples t-test and McNemar's test
Results: the Go-Gn [P=0.029] and Me-N [P=0.021] distances significantly increased following the use of appliance while overjet [P<0.0001], absolute overbite [P=0.002] and the Wits appraisal [P=0.019] significantly decreased. Other understudy angles did not change significantly
Conclusion: multi P[registered sign] appliance decreases the jaw base discrepancy and corrects the overjet and overbite
ABSTRACT
Early childhood caries [ECC] is a severe type of dental caries affecting infants and pre-school children. Because of the infectious nature of the disease, the immunologic response by the host plays an essential role in its development. This study investigated the association between the presence of salivary sCD14 and ECC. This study was carried out on 40 healthy children, of whom 20 were caries-free [CF] and 20 had ECC, within the ages of 36 to 71 months. Unstimulated saliva of the children was collected with disposable needle-less syringe from buccal and labial vestibules. Seven children with ECC received complete treatments. Saliva was collected for a second time after 3 months from this group. The sCD14 levels in salivary samples were analyzed by ELISA method. Mean concentrations of sCD14 in ECC and CF groups were 57.82 and 31.92 ng/ml respectively [p=0.008]. After three months, the mean concentration of sCD14 among the treated children decreased to 11.38 ng/ml, which was significantly lower compared to that of ECC children before intervention [p<0.001], and also CF children [p<0.05]. The increased levels of sCD14 can be considered as a marker of inflammation and innate immune response during ECC