ABSTRACT
The Tatural herbs have biological activities that benefit in the treatment of many diseases which infect the human. The extracts of natural herbs were investigated for their Hyperglycemic, hyperlipidemic effects and Oxidative Status as well as histological - examination of pancreas section in normal and alloxane induced diabetic rats. The three tested herbal extracts [turmeric, ginseng and rosemary] at a dose of 300 mg/kg body weight were incorporated with the standard diet of diabetic rats. Hyperglycemia induced by alloxan cause strong increase level of glucose by [141.41%], as well as progressive decrease in plasma insulin level. Treatment with turmeric and ginseng herbal extracts in general seems to affect the physiological role of insulin, as it caused slight increase in plasma insulin level. Blood hemoglobin and liver glycogen content significantly decreased in diabetic rats, Treatment with turmeric and ginseng extract showed an improvement in their levels. The values of lipids profile were significantly increased in diabetic rats except HDL-C. A significant reduction in the lipid profile values occurred with the treatment of the three herbal extracts. With the respect to MDA and IRR ratio alloxan induced diabetic caused significant increase in their levels compared with healthy control. Treatment with turmeric, ginseng and rosemary extract reflected this increase. Also diabetic caused significant decrease in plasma vit. E; erythrocytes, SOD activity and liver GSH. Vitamin E value affected by the treatment of the herbal extracts. Histological examination of pancreas section in diabetic rats showed reduction in the number of islet cells and necrosis with many pyknotic nucli. Treatment of diabetic rats with the three herbal extracts caused Changes represented by increase of islet cells number?
ABSTRACT
The extracts of turmeric, ginseng and rosemary were investigated for their biochemical effects on liver and t kidney functions as well as histological examination of liver and kidney sections in normal and alloxane induced diabetic rats
Material and methods: the three tested herbal extracts at a dose of 300 mg/kg body weight were incorporated with the balanced diet of diabetic rats
Results: Hyperglycemia induced by alloxan caused a progressive increase in plasma urea and creatinine levels, diabetic rats were affected by the treatment with the three herbal extracts to show highly significant reduction in plasma urea levels by about 42.54%, 41.39% and 40.13% for turmeric, ginseng and rosemary extracts respectively as well as marked reduction in plasma creatinine. Alloxan induced diabetes caused highly significant decrease in the level of total proteins, albumin and A/G ratio, also caused significant increase in ALT, AST and ALP activities. The picture showed significant improvement by the treatment with the three herbal extract in diabetic rats. Also treatment with the extracts caused significant increase of the liver GST activity and did not affect the DNA content of diabetic rats. Histological examination of normal liver and kidney sections showed normal structures. Diabetic rats liver sections showed dilated and inflammation blood vessel, areas of fibrous tissue. Kidney sections of diabetic rats exhibited glomerulosclerosis with basal membrane thickening
Conclusion: treatment of diabetic rats with the three tested herbal extracts caused a moderate degree of recovery in both liver and kidney sections?
ABSTRACT
Was two folds to: explore women's practices and coping patterns with menopausal symptoms through: [a] Recognizing women's symptoms associated with menopause, [b] Assessing women's knowledge regarding menopause, [c] Identifying women's health related coping practices during menopause, and to develop instructional guidelines for women as a model for better coping with menopause. A convenient sample of total 190 menopausal women, aged <40 to >50 years was selected from three maternal and child health centers and three health centers representing different Urban districts in Cairo. Home visits in the same areas were conducted. Three tools were used for data collection [1] Interviewing questionnaire format [2] Lifestyle Behavior Scale, and [3] Coping Patterns scale. Findings indicated that the MW always had hot flushes [44.2%], irregular heart beats and joints and muscles pain had same percentages [41.1%]. 56.8% of them had night sweating. feeling tired and anxiety represented 65.8% and 57.9%, respectively. A high statistically significant correlation was found between women's health related practice and coping patterns with the MS and vice versa, and highly statistically significant correlation between women' education and income and their coping pattern. While, a statistically significant correlation was existed between age and coping pattern. However, Meanwhile, highly statistical significant correlation existed between women' knowledge related to menopause their coping with menopause. The most common symptoms among MW include hot flushes, muscle and joint pain, sweating and irregular heart beats, besides obesity [grade I], in addition to feeling tired, anxiety and fear from future. MS affected most of the subjects' marital relationships and sexual relations. The MW were able to adapt/manage the physical symptoms efficiently, while they failed in relieving psychological and sexual symptoms, and reducing weight. Lack of menopause related knowledge, sources of health education and increased women's tolerance towards adaptation for any complain decreased the women's tendency to express suffering. The CHNs should do the followings in all community health settings: Encourage MW to perform periodical examination. Carry out related health education/counseling sessions including coping strategies. Freely distribute the developed instructional guidelines to all MW. Utilize officially a T.V. channel and broadcasting as a mass media, associated with real life examples. Encourage women in coping and helping family members to become supportive with MW through home visiting / outreach services, beside update and sharpen her knowledge through On-Job-Training programs and others