Coagulation disturbances in pregnancy and post delivery period in Sudan

Coagulation problems during pregnancy and after delivery are major health problems leading to fatal complications. Coagulation complications in pregnancy are related to hypertension [PIH], placenta previa or gestational diabetes as well as some chronic problems that effect pregnancy like heart disease and asthma. The study was intended to measure the coagulation profiles, prior and post delivery, to find out coagulation hazards among those ladies compared to non-pregnant ladies as control group. A descriptive comparative study was conducted from Jan to June 2007 using 70 blood samples obtained from non-pregnant ladies [control] and 140 blood samples obtained from 70 ladies during pregnancy and after delivery. The coagulation tests [prothrombin time, activated partial thromboplastin time, thrombin time and platelets count] were performed on all samples by the same manner. Results showed that prothrombin time, activated partial thromboplastin time, thrombin time and platelets count prior and post delivery were significantly decreased compared to control, unlike platelets which were increased rather than in control without statistical significance. Also the coagulation profiles were significantly affected by the type of delivery [cesarean section and normal], while not affected by mothers' age, circumcision, history of abortion and diabetes mellitus. There is observable effect of weight and contraceptive. It is concluded that the coagulation profile prior and post delivery were significantly decreased compared to control, while platelets were increased more than that counted in control. It is recommended to investigate pregnant ladies for coagulation profile before and after delivery and treatment should be offered to ladies with high risk

Evaluation of laboratory procedures used for screening food handlers in the Sudan

The objective of this study was to find a suitable laboratory procedure for screening Sudanese food handlers for Intestinal parasites. Routine direct smear, formal ether and floatation techniques were compared. A total of 1500 food handlers who presented for annual checkups were screened for Intestinal parasites by direct faecal examination, formal ether concentration technique and floatation technique. The sensitivity of both the direct smear and the floatation technique was 64.2%, while the specificity of both methods was 100% when using the formal ether technique as the standard technique. There was a statistically significant difference of a p-value < 0.05. When regarding the direct smear as the standard technique, the sensitivity of the floatation technique was 39.8% while the specificity was 94%. In conclusion the formal ether concentration technique is the more suitable technique for a high sensitivity and feasible application in different regions of Sudanconcluded that the clinical presentation and MRI findings did not differ much from what is reported worldwide

Coagulation disturbances in pregnancy and post delivery period in Sudan

Coagulation problems during pregnancy and after delivery are major health problems leading to fatal complications. Coagulation complications in pregnancy are related to hypertension [PIH], placenta previa or gestational diabetes as well as some chronic problems that effect pregnancy like heart disease and asthma. The study was intended to measure the coagulation profiles, prior and post delivery, to find out coagulation hazards among those ladies compared to non-pregnant ladies as control group. A descriptive comparative study was conducted from Jan to June 2007 using 70 blood samples obtained from non-pregnant ladies [control] and 140 blood samples obtained from 70 ladies during pregnancy and after delivery. The coagulation tests [prothrombin time, activated partial thromboplastin time, thrombin time and platelets count] were performed on all samples by the same manner. Results showed that prothrombin time, activated partial thromboplastin time, thrombin time and platelets count prior and post delivery were significantly decreased compared to control, unlike platelets which were Increased rather than in control without statistical significance. Also the coagulation profiles were significantly affected by the type of delivery [cesarean section and normal], while not affected by mothers> age, circumcision, history of abortion and diabetes mellitus. There is observable effect of weight and contraceptive. It is concluded that the coagulation profile prior and post delivery were significantly decreased compared to control, while platelets were increased more than that counted in control. It is recommended to investigate pregnant ladies for coagulation profile before and after delivery and treatment should be offered to ladies with high risk