ABSTRACT
Seroprevalence of HCV antibodies [anti-HCV] and HBV antigens [HBs Ag] were investigated in 33 patients with proved fascioliasis and 20 normal subjects control. In the whole fasciolial patients, 75.8% and 36.4% showed anti-HCV and Hbs Ag positivity, while in controls they were 15% and 5%, respectively. Mixed infection with HCV and HBV was found in about 30% of fasciolial patients. However, the HCV virus was still present [HCV-RNA antigen] in only about 24% of the whole fasciolial patients and 32% of those having anti-HCV positivity. Thus fasciolial patients showed higher of having viral hepatitis than non fasciolial group. It could be concluded that fasciolial patients are good candidate for HCV rather than HBV infection and there is a high association between fascioliasis and HCV infection which accelerates the dearrangement of liver function and the occurance of complications