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Rev. bras. anal. clin ; 39(2): 115-118, abr.-jun. 2007. tab, graf
Article in Portuguese | LILACS | ID: lil-477004

ABSTRACT

A presença do cateter venoso central (CVC) no organismo aumenta o risco de colonização de microrganismos podendolevar a disseminação microbiana principalmente em internados de Unidade de Terapia Intensiva. O objetivo do trabalho foi determinar os microrganismos mais freqüentes e o perfil de suscetibilidade aos antimicrobianos em ponta de CVC provenientes de pacientesdo Hospital Pronto Socorro Municipal Dr. Humberto Maradei Pereira, Belém-PA, entre janeiro-2003 a dezembro-2004. Foram executadas 61 culturas e antibiogramas de pontas de CVC pelo método semiquantitativo de Maki. A identificação dos agentes e os testes de suscetibilidade seguiram metodologias convencionais e sistema automatizado ATB-Expression. Foram positivas 56(91,8%) culturas com prevalência de Pseudomonas aeruginosa 26,8%, Staphylococcus aureus 21,4% e Staphylococcus coagulase negativa-SCN 16,1%. Os isolados de P. aeruginosa demonstraram maior sensibilidade para Colistina (100%), Fosfomicina (93,3%), Imipinem e Meropenem (80%) tendo resistência acima de 40% aos demais antimicrobianos testados. Foram encontradas cepas oxacilina-resistentes de 41,7% para S. aureus e 11,1% para S. coagulase negativa sendo todas sensíveis à Vancomicina. Isolados de S. aureus e SCN apresentaramsensibilidade acima de 70% à Nitrofurantoína, Vancomicina, Teicoplanina, Minociclina, Quinopristina-Dalfopristina e Ácido Fusídico tendo revelado elevada resistência para Clindamicina, Cotrimoxazol, Penicilina G, Eritromicina, Rifampicina, Norfloxacina e tetraciclina.


The presence of the central veined catheter in human organism increases the risk of colonization of microrganisms mainly in admitted patients the Intensive Care Unit. The objective of this assignment was to determine the most frequent microrganisms and the susceptibility profile to the antimicrobial in tip of veined catheter originating from patients who were admitted in “Hospital Pronto Socorro Municipal Dr. Humberto Maradei Pereira”, Belém – PA, from January 2003 to December 2004. Sixty-one culture and antibiograms of catheter were analyzed to the semi quantitative method of Maki. The agent’s identification and the susceptibility tests followed conventional methodologies and ATB – Expression authorized system. They were positive 56(91.8%) cultures with prevalence of Pseudomonas aeruginosa 26.8%, Staphylococcus aureus 21.4% and Staphylococcus coagulase negative-SCN 16.1% The stumps of P. aeruginosa demonstrated a larger sensibility for Colistin (100%), Fosfomicin (93.3%), Imipenem (80%) and Meropenem (80%), there was a resistance of more than 40% in the other tested antimicrobial. Among the Staphylococcus, there were oxacilin-resistant stumps of 41.7% for S. aureus and 11.1% for Staphylococcus negative coagulase, but all of them were sensitive to vancomicin. The stumps of S. aureus and Staphylococcus negative coagulase presented sensibility above 70% to nitrofurantoin, vancomicin teicoplanin, minociclin, quinopristin-dalfopristin and fusidic acid, which revealed high resistance (above 50%) to clindamicin, cotrimoxazol, penicillin G, eritromicin, rifampicin, norfloxacin and tetraciclin.


Subject(s)
Humans , Bacterial Infections , Catheterization, Central Venous , Catheters, Indwelling , Pseudomonas aeruginosa , Drug Resistance, Multiple
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