Nurses' Perception of Accreditation, Awareness and Performance of Infection Control in an Accredited Healthcare System / 간호행정학회지

PURPOSE: This study was conducted to provide basic data necessary to develop a program to improve infection control by examining nurses' perception of accreditation and by identifying its relationship with awareness and performance of infection control. METHODS: This cross-sectional study was performed using questionnaires. Data were collected from 210 nurses who were working at one hospital between May 14 and May 19, 2015. Data were analyzed using SPAW. RESULTS: The mean score for nurses' perception of accreditation was 3.10 points out of 5 points. Score for awareness of infection control was 4.63±0.39 points and for performance of infection control, 4.39±0.39 points. There were significant positive correlation among perception of accreditation, awareness of infection control, and performance of infection control. In the regression analysis, performance of infection control was influenced by awareness of infection control which accounted for 42.6% of the variance. It also showed additional improvement of 1.4% of the variance by when perception of accreditation was added. CONCLUSION: The result of this study show that nurses' perception of accreditation is relatively positive and that performance of infection control is highly enhanced according to nurses' positive recognition of accreditation as well as attaching importance to accreditation.

Integrin Expression and Apoptotic Cells in Dermal Melanocytic Tumors / 대한피부과학회지

BACKGROUND: Many mammals normally have a population of dermal melanocytes but these are not found in man, In humans, persistent dermal melanocytes can occur in the Mongolian spot, the nevus of Ota, and the blue nevus. Mongolian spot develops in the fetal or neonatal time and disapperars almost invariably during childhood. In contrast, nevus of Ota and blue nevus are not usually present at birth and persists in adult life. Recently, it was established that apoptosis can be involved in the development of melanocytes. The integrins mediate cell-cell and cell-matrix interactions, and apoptosis can be induced by disruption of cell-matrix interactions. OBJECTIVE: The purpose of this study was to investigate the expression of integrins (a2, a3, ar) and in situ detection of fragmented DNA in Mongolian spot, nevus of Ota, and blue nevus. METHODS: Formalin-fixed and paraffin-embedded tissues from 8 cases of Monglian spot, 5 cases of nevus of Ota, and 4 cases of blue nevus were immunolabelled with monoclonal antibodies TM directed against az, ay, and av integrin, and stained with ApopTag in situ using an Apoptosis Detection kit. The cases of Mongolian spot were divided into two groups in which group A represented the the cases of more than 45 melanocytes and group B represented the cases of less than 10 melanocytes in a tissue section of 4-mm taken from punch biopsy specimens. RESULTS: Blue nevi showed az and e integrin expressions in dermal melanocytes and weak to negative staining of g v integrin in comparison with all positive expressions of a z, a s, and g y integrin in A group-Mongolian spots and nevi of Ota. The B group-Mongo]ian spots showed the continuous expressions of a z and a y integrin with negative expressions of a v integrin. The ApopTag kit staining was all negative in the Mongolian spots, nevi of Ota, and blue nevi. CONCLUSION: Our results support the view that dermal melanocytic tumors, such as the Mongolian spot, the nevus of Ota, and the blue nevus, might be induced by the disturbance or inhibition of the apoptotic process of the melanocytes, and that the spontaneous disappearance of the Mongolian spot may not be related to the apoptosis.

A Case of Xanthogranuloma in an Adult / 대한피부과학회지

Clinically adult-onset xanthogranuloma is somewhat different to that of juvenile xanthogranuloma. There seems to be no definitive sites of predilection and concomitant extracutaneous lesions, and spontaneous resolution does not occur in the adult form. The lesions of the adult form are usually asymmetric or solitary. We describe an adult with a solitary xanthogranuloma on the left shoulder. Histological findings of this case show minor differences from juvenile xanthogranuloma but immunohistochemical findings were very similar to those of juvenile xanthogranuloma.

A Case of Trichonodosis / 대한피부과학회지

Trichonodosis(knotted hair) is a disorder of the hair shaft that can comprise a single or double knot. Reports of trichonodosis are not cornmon in dermatological literature, but it is generally considered not to be rare. Two varieties of trichonodosis have been described. A rare type occurs in association with abnormally growing scalp and body hair that tends to splinter and fracture. A more comrnon form occurs when normal hair is subjected to rnechanical forces, such as combing and brushing. Trichonodosis occurs exclusively in persons with curly or kinky hair. We report a patient with short, straight hair and trichonodosis. The most likely cause in our patient is trauma as a result of continual rubbing of hairs.

A Case of Malignant Histiocytosis

Malignant histiocytosis is a rare, usually fatal malignant neoplasm of reticuloendothelial systems. The disease is associated with fever, malaise, weight loss, hepatosplenomegaly, lymphadenopathy, pancytopenia, jaundice, and purpura. A 44-year-old female patient is described who had multiple, purple crusted nodules and plaques in the skin. In the laboratory study, pancytopenia was noted on the peripheral blood. In addition many atypical histiocytes were seen on the bone marrow aspiration. A lesional biopsy showed nodular infiltrations of atypical histiocytes in the dermis and some erythrophagocytosis was seen. Immunohistochemically, the histiocytes were weakly stained for lysozyme and α-l-antichymotrypsin, but were unstained for S-100 protein, cytokeratin, CEA(carcinoembryonic antigen), pan T/B marker CD30(ki-1), UCHL-1 LCA(leukocyte common antigen), and α-l-antitrypsin.