Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add filters








Language
Year range
1.
Article in English | IMSEAR | ID: sea-59552

ABSTRACT

Under in vitro conditions N-alpha-tosyl L-arginine methyl ester (TAME) induced a concentration dependent contractile response on ileal strips with EC50 of 4.3 x 10(-5) M as compared to acetylcholine which induced sustainable contractions with EC50 of 3.2 x 10(-6) M. The present study is the first to demonstrate that TAME is a potent constrictor of non-airway smooth muscle.


Subject(s)
Animals , Bufonidae , Ileum/drug effects , Muscle Contraction/drug effects , Muscle, Smooth/drug effects , Tosylarginine Methyl Ester/pharmacology
SELECTION OF CITATIONS
SEARCH DETAIL