ABSTRACT
Hombre de 34 años, con una semana de evolución de fiebre, cefalea y compromiso del estado general, a lo que se agregó posteriormente dolor en hipocondrio derecho, coluria e ictericia de piel y mucosas. El laboratorio evidenció leucopenia, plaquetopenia, hiperbilirrubi-nemia y gran aumento de las transaminasas. Se informó VDRL positivo » y más tarde un test de MHA-TP positivo. El estudio para hepatitis A, B, C, citomegalovirus y virus de Epstein Barr fue negativo, la IgG para virus de hepatitis E fue positiva. La biopsia hepática demostró alteraciones concordantes con hepatitis sifilítica. El paciente recibió penicilina benzatina 2.400.000 U.I. una vez a la semana durante tres semanas con buena respuesta. Después del alta se conoció reacción de polime-rasa en cadena positiva para el virus de inmuno-deficiencia humana (VIH). Este caso ejemplifica una manifestación poco usual de la sífilis secundaria, a la cual atribuimos la complicación hepática, que se presenta prácticamente pura en un paciente infectado con el VIH, dato conocido sólo después del alta
Subject(s)
Humans , Male , Adult , Hepatitis, Viral, Human/etiology , HIV Infections/complications , Syphilis/complications , Hepatitis, Viral, Human/drug therapy , Penicillin G Benzathine/administration & dosage , Treponema pallidum/pathogenicityABSTRACT
We report a 29 years old female presenting with fever and painful infiltrated erythematous and violaceous plates with pseudo vesicles in the surface, located in both arms, four days after having suffered a tonsillitis. She was admitted with the diagnosis of Sweet syndrome and the lesions disappeared spontaneously. Two months later, she presented with a similar condition, again after an upper respiratory infection. Five months later, she was admitted with arthralgias with positive rheumatoid factor and antinuclear antibodies. Three years after the first admission, she was admitted with an acute glomerulonephritis and renal failure after another upper respiratory infection. Sweet syndrome was described in 1964 and, although initially considered benign, its association with inflammatory diseases or cancer has been reported
Subject(s)
Humans , Adult , Female , Arthritis, Rheumatoid/complications , Renal Insufficiency, Chronic/complications , Sweet Syndrome/complications , Aspirin/therapeutic use , Arthralgia/diagnosis , Arthralgia/drug therapy , Glomerulonephritis/diagnosis , Glomerulonephritis/etiology , Diagnosis, Differential , Hematocrit , Renal Dialysis , Renal Insufficiency, Chronic/etiology , Renal Insufficiency, Chronic/therapy , Sweet Syndrome/diagnosisSubject(s)
Humans , Female , Middle Aged , Forearm , Pilomatrixoma/diagnosis , Clinical Laboratory Techniques , Pilomatrixoma/surgery , Skin TransplantationABSTRACT
Cutaneous polyarteritis nodosa is a benign form of the disease with cutaneous involvement and occasional systemic manifestations. We report a 51 years old man presenting with malaise, arthralgia, myalgia and nodular, erythematous and painful skin lesions in both legs. The pathological study of these lesions showed a polyarteritis. During hospital stay there was a mild remission of the disease without treatment, but it reappearence during follow lead to the use of prednisone
Subject(s)
Humans , Male , Middle Aged , Polyarteritis Nodosa/diagnosis , Skin Manifestations , Polyarteritis Nodosa/pathology , Polyarteritis Nodosa/drug therapyABSTRACT
Se presenta un caso de paraganglioma vesical, un tumor poco frecuente del sistema APUD
Subject(s)
Humans , Female , Adult , Apudoma/diagnosis , Paraganglioma/diagnosis , Urinary Bladder Neoplasms/diagnosis , Apudoma/pathology , Apudoma/secondary , Apudoma/surgery , Laparotomy , Paraganglioma/pathology , Paraganglioma/secondary , Paraganglioma/surgery , Prognosis , Urinary Bladder Neoplasms/surgeryABSTRACT
Las dermatosis neutrofílicas comprenden una serie de enfermedades que histológicamente comparten un infiltrado de neutrófilos prominente y que parecen tener un mecanismo patogénico común. En este artículo presentamos una serie clínica de pacientes con esta dermatosis y se discuten algunos aspectos clínicos, histopatológicos y patogénicos de relevancia