ABSTRACT
Objective: To study Bone density and serum osteocalcin level in children with acute lymphoblastic leukemia
Methods: Serurn osteocalcin and DXA scan were evaluated in 45 children with ALL, 15 at diagnosis and before starting chemotherapy, 15 during chemotherapy and 15 after completing their treatment regimen
Results: From the total 45 patients, 23 [51.1%] had low osteocalcin level and 36 [80%] had low bone rnineral density [48% had osteopenia and 32% had osreoporosis]
Conclusion: Musculoskeletal abnormalities are present in children with ALL at diagnosis, during treatment] and persist as long-term squeal after treatment
ABSTRACT
Objective: to study Bone density and serum vitamin D level in children with acute lymphoblastic leukemia [ALL]
Methods: serum vitamin D level and DXA scan studying bone density were evaluated in 45 children with ALL, 15 at diagnosis and before starting chemotherapy, 15 during chemotherapy and 15 after completing their treatment regimen
Results: from the total 45 patients, 33 had vitamin D deficiency, 7 had vitamin D insufficiency and 36 - 80% had low bone mineral density 48% had osteopenia and 32% had osteoporosis
Conclusion: musculoskeletal abnormalities are present in children with ALL at diagnosis, during treatment, and persist as long-term squeal after treatment