ABSTRACT
The conceptions products obtained from 20 patients with repeated abortions and chronic toxoplasmosis were examined histopathologically comparing the results with those of ten Toxoplasma seronegative patients. The results showed significant association between chronic toxoplasmosis and diffuse failure of growth of placental villi
Subject(s)
Toxoplasmosis , Chronic Disease , AbortionABSTRACT
200 women with history of abortion and 100 women with history of uneventual pregnancies were investigated serologically for anti-Toxoplasma antibodies using both the indirect haemagglutination test and the Sabin-Feldman dye test. Our results indicated a role for the first test in seroepidemiological surveys and for routine work. The second test may be reserved for cases with negative haemagglutination test in the presence of strong suspicion of toxoplasmosis
Subject(s)
Serologic Tests , Hemagglutination TestsABSTRACT
The histopathological picture of Toxoplasma gondii RH strain [virulent] and Beverley strain [a virulent] was experimentally studied in mice. Nearly all the internal organs and tissues showed pathological changes ranging between the mild congestion to the severe degeneration. However, the changes were more serious in mice infected with RH strain than those infected with Beverley strain. The lungs showed massive consolidation and severe congestion. The heart showed hyaline degeneration of a cardiac muscle fibers.Focal areas of necrosis were seen in the liver, spleen and kidneys which were enlarged as well as in the cerebral cortex of the brain. The bone marrow and skeletal muscles were infiltrated by mononuclear inflammatory cells. The eyes showed mononuclear inflammatory cells in the retina consisted mainly of lymphocytes and the photo receptors were damaged. In congenital toxoplasmosis the brain showed perivascular mononuclear inflammatory infiltrate as well as multiple areas of necrosis. Microglial nodules were sometimes seen. The eyes showed no pathological lesion