study to evaluate the effect of ratio of donor kidney weight to recipient body weight on renal graft function

To study the effect of the ratio of donor kidney weight [dkw] to recipient body weight [rbw] on short and long term graft function in live donor kidney transplant patients. It was a prospective study of 79 live donor kidney transplant recipients. Patients were divided into three groups depending on the ratio of dkw in grams to rbw in kilograms. Serum creatinine in milligrams percent on the day of surgery, 7[th] day, 1 month, 6 months, 1 year, and 3 years after the surgery was recorded and their means compared. The comparison showed that the decrease in mean creatinine level was more in group three patients as compared with group 2 and one patients at 7 days [1.04, 1.44 and 1.59 in group 3, 2 and 1 respectively] and 30 days [1.12, 1.36 and 1.45 in group 3,2 and 1 respectively], showing that higher dkw/rbw ratio is beneficial with respect to the early graft function. However this decrease was not statistically significant [P value -0.256 and 0.358 respectively on 7[th] and 30[th] day]. Furthermore long-term function was not different among these three groups. The ratio of dkw to rbw does not have a significant effect on long-term graft function inspite of an early improvement in the function with increased dkw to rbw ratio

Isolated Renal Mucormycosis in a Healthy Immunocompetent Patient: Atypical Presentation and Course

Isolated renal mucormycosis is rarely identified and has been described in only a handful of cases. We hereby report a case of isolated renal mucormycosis with an atypical presentation in an immunocompetent patient with no identifiable risk factors. A 30-year-old nondiabetic male presented with a poorly functioning right kidney with minimal constitutional symptoms. The patient underwent a right simple nephrectomy. Histopathology revealed necrotizing xanthogranulomatous pyelonephritis with mucormycosis. The postoperative period was uneventful and the patient was managed without any antifungal administration. We hereby emphasize that renal mucormycosis can affect immunocompetent healthy adults without any previously known risk factors and that asymptomatic patients with no evidence of fungemia or disseminated disease can be managed without administration of intravenous amphotericin.