ABSTRACT
El síndrome de boca urente (SBU) es una condición enigmática porque la intensidad de los síntomas rara vez se corresponde con los signos clínicos de la enfermedad. Los síntomas incluyen ardor bucal, boca seca, dolor, cambios en los hábitos alimenticios, graves síntomas de la menopausia, y problemas no específicos de salud, entre otros. SBU es más frecuente en las mujeres posmenopáusicas con relación mujer/hombre de 7:1. La etiología del SBU es multifactorial, como los cambios hormonales (menopausia), las carencias nutricionales y alteraciones del gusto por nombrar algunos. SBU es un reto con respecto al diagnóstico y al manejo. El presente artículo analiza algunos de los acuerdos recientes de la etiopatogenia de SBU, así como el papel de la gestión farmacoterapeutica en este trastorno.
Burning mouth syndrome (BMS) is an enigmatic condition because the intensity of symptoms rarely corresponds to the clinical signs of the disease. Symptoms include oral burning, dry mouth, pain, changes in eating habits, severe menopausal symptoms, and non specific health problems etc. BMS is most prevalent in postmenopausal women with female: male ratio of 7:1. The etiology of BMS is multifactorial such as hormonal changes (menopause), nutritional deficiencies and taste disturbances to name a few. BMS is a challenge to diagnose and manage. The present article discusses some of the recent understanding of etiopathogenesis of BMS as well as the role of pharmacotherapeutic management in this disorder.
Subject(s)
Humans , Burning Mouth Syndrome/epidemiology , Burning Mouth Syndrome/etiology , Burning Mouth Syndrome/therapy , GlossalgiaABSTRACT
OBJECTIVE: To review the literature and present a case of Gorlin´s syndrome with situs inversus. RESULTS AND DISCUSSION: Together with the major features, a great number of processes considered as minor features have also been described in the Gorlin´s syndrome. The latter includes numerous skeletal, dermatology related and neurological anomalies among others. In the present clinical case many criteria allowed a diagnosis of Gorlin´s syndrome, but for the first time this unique finding of situs inversus is seen with this syndrome. CONCLUSION: However, further research is needed to confirm the association between situs inversus and Gorlin´s syndrome.
OBJETIVO: Revisar a literatura e apresentar um caso de síndrome de Gorlin com situs inversus. RESULTADOS E DISCUSSÃO: Conjuntamente com os aspectos principais, um grande número de processos considerados menores têm sido descritos na síndrome de Gorlin. Entre outras, numerosas anomalias esqueletais, dermatológicas e neurológicas têm sido relatadas. No presente caso clínico, muitos critérios permitiram o diagnóstico da síndrome de Gorlin, porém, pela primeira vez relata-se a ocorrência deste achado único, o situs inversus. CONCLUSÃO: Entretanto, pesquisas adicionais são necessárias para confirmar a associação entre situs inversus e síndrome de Gorlin.