ABSTRACT
Introduction: Diabetes mellitus is the most common metabolic disorder complicating pregnancy. About 1-14% of all pregnancies are complicated by diabetes mellitus. Metabolic complications are frequently occurring complication in infants of diabetic mother
Objective: To determine the frequency of metabolic complications in infant of diabetic mother
Study Design: Cross sectional study
Duration of Study: January 2016 to June 2016
Setting: Department of Pediatric Medicine Unit-1, Allied Hospital, Faisalabad. Sample size: The total sample size is 295 cases
Sampling Technique: Non probability purposive sampling
Methodology: After taking permission from ethical committee of the hospital total 295 patients who fulfilled the inclusion and exclusion criteria were enrolled in the study. Informed consent was obtained from parents. Demographic details like name, age, gestational age at birth and gender was obtained. Neonates were assessed for presence of metabolic complications by drawing 3 ml venous blood and sending it to pathology lab for blood glucose levels, serum calcium and magnesium. Hypocalcaemia, hypomagnesaemia, and hypoglycemia were assessed as per operational definition
Results: In our study, out of 295 cases, mean age was calculated as 14.09 +/- 4.75 days, 46.44%[n=137] were male while 53.56%[n=158] were females. Frequency of metabolic complications in infant of diabetic mother was recorded as 18.31%[n=54], 7.11%[n=21] had hypomagnesemia and 39.66%[n=117] had hypoglycemia
Conclusion: We concluded that the frequency of hypoglycemia is more common in infant of diabetic mother. However, early diagnoses and start of early treatment may help in reduction of mortality and morbidity of these patients
ABSTRACT
To determine the frequency of Hepatitis B Virus infection and clinical profile among children with chronic liver disease. Descriptive, Cross sectional Study. The study was conducted in the Department of Pediatric Medicine Allied Hospital Faisalabad from 1[st] June 2007 to 31[st] May 2009. The data of all patients admitted with chronic liver disease during the study period was recorded for age, sex, gender, risk factors, and socioeconomic factors, duration of disease, clinical signs and relevant investigations. A total of hundred patients with chronic liver disease were studied. Among them 54% were male and 46% were female. 15% of patients had positive history of blood transfusion. Hepatitis B seropositivity was found to be 30% in children with chronic liver disease tested by HBsAg in serum. Chronic HBV infection is serious viral disease that can lead to cirrhosis and hepatocellular carcinoma. Hepatitis B Vaccine should be given to all neonates regardless of maternal HBsAg status to prevent the disease