ABSTRACT
Background: thrombolysis In Myocardial Infarction [TIMI] risk score predicts adverse clinical outcomes in patients with non-ST-elevation acute coronary syndromes [NSTEACS]. Whether this score correlates with the coronary anatomy is unknown
Objective: to determine the frequency of low, moderate and high TIMI risk score in patients of NSTEACS and to compare the frequency of two vessel coronary artery disease on angiography with low, moderate and high TIMI risk scores in patients of NSTE-ACS
Study design: this was a cross sectional study
Setting: department of Cardiology, Gulab Devi Chest Hospital, Lahore
Duration: six months
Patients and Methods: total 170 patients were included in the study. Patients' selection was done with the help of a pre-defined inclusion and exclusion criteria. TIMI risk score was calculated for each patient and patients were categorized into low, moderate and high risk groups [as per operational definition]. Patients were further evaluated with coronary angiograms to assess the double vessel CAD. All angiographies were performed by a single physician. Data analysis was done on SPSS version 17
Results: mean age of our patients was 54.81 +/- 10.55 years. Gender distribution shows that there were 106[62%] male and 64[38%] female patients. TIMI score risk classification showed that among 50[29.4%] patients TIMI risk score was low, among 107[62.9%] patients it was moderate and in 13[7.6%] patients it was high. There were 105[62%] patients who had two vessel coronary artery disease. Among 105 patients who had two vessel coronary artery disease, 25[23.8%] had low TIMI score, 69[65.7%] had moderate and 11[10.5%] of the patients had high TIMI score
Conclusion: in patients with non-ST-elevation acute coronary syndrome undergoing cardiac catheterization, the TIMI risk score is significantly associated with two vessel coronary artery disease. So it should be recommended that a routine invasive strategy be carried in patients with moderate or higher TIMI risk score