Clinicopathological analysis of odontogenic cysts in a selected Pakistani population

The cysts of the jaw are broadly classified as odontogenic and non-odontogenic. The odontogenic cysts are pathological fluid filled cavities lined by odontogenic epithelium and further sub-classified as inflammatory and developmental. The objective was to determine the types, frequency, distribution, and demographic characteristics of odontogenic cysts in our setup. This 8 years retrospective study [from January 2003 to December 2010] was conducted at Histopathology department of Armed Forces Institute of Pathology, Rawalpindi [Pakistan]. The histopathology record of odontogenic cysts were reviewed for age, gender, site, associated tooth and histopathological diagnosis. The data was analysed by using SPSS soft ware package version 17. The data revealed that periapical, dentigerous and odontogenic keratocysts were the most commonly reported odontogenic cysts which reported in the age range of 4 to 72 years [mean 29.09 +/- 13.53 years]. Amongst them 67.7% were males and 32.3% females with peak incidence in the 2[nd] and 3[rd] decades. The association of age and teeth with different type of cysts was statistically significant while gender association was insignificant although having predilection for males. None of the case of odontogenic keratocyst was found in deciduous teeth. The statistically significant association of different types of Odontogenic cysts with the age, site, teeth and male prevalence reveals that demographic knowledge can be helpful in early diagnosis and their prompt treatment

Clinicopathalogical analysis of benign salivary gland tumours: a study of 242 cases at AFlP Rawalpindi [Pakistan]

Objective: to analyze the clinicopathological aspects of benign salivary gland tumors. Materials and Methods: This descriptive case series study was carried out from Jan 2003 to Dec 2009 at Armed Forces Institute of Pathology Rawalpindi, [Pakistan]. All cases of benign salivary gland tumors were reviewed and their diagnoses were reconfirmed. The data regarding all the major and minor salivary gland tumor was analyzed using computer soft ware program SPSS [version 17]. The descriptive statistics and frequency was calculated for type of tumors, age, gender, site and size. Association of these parameters with the type of tumor was calculated by using chi square test. Results: the most common histological tumor type found was pleomorphic adenoma, followed by Myoepithelioma. All these cases presented between 12 and 85 years of age [mean 39.7 +- 16.91] mostly in the 3rd and 4th decades of life with 48.7% males and 51.3% females respectively. The most frequent site involved by these tumors were parotid gland [66.5%]. Submandibular gland, minor salivary glands of palate and lip were the other sites involved, but none of the tumor was found in sublingual gland. The tumor size ranged between 0.4 to 18 cm with maximum variation in Pleomorphic adenoma and myoepithelioma. Conclusion: benign salivary gland neoplasm are more common than their malignant counterparts. They occur mostly in 3rd and 4th decade. Parotid gland is the most common site and pleomorphic adenoma remains the most common bengin salivary gland neoplasm followed by myoepithelioma.