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J Indian Med Assoc ; 2007 Apr; 105(4): 177-8
Article in English | IMSEAR | ID: sea-103417

ABSTRACT

Racemates are fixed-dose combinations of stereoisomers. Each isomer may have different pharmacokinetic or pharmacodynamic properties. Recent research has allowed appreciation of the need to purify racemates and develop useful unichiral molecules. Some examples are: S-amlodipine besylate, S-atenolol, S-metoprolol succinate, S-pantoprazole sodium and R-ondansetron hydrochloride.


Subject(s)
Chemistry, Pharmaceutical , Drug Design , Drug Industry , Drug Prescriptions , Drug-Related Side Effects and Adverse Reactions , Humans , Molecular Conformation , Molecular Structure , Pharmacokinetics , Pharmacology , Stereoisomerism
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