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Rev. bras. cardiol. (Impr.) ; 27(4): 260-266, jul.-ago. 2014. tab, graf
Article in Portuguese | LILACS | ID: lil-746693

ABSTRACT

Fundamentos: A presença de diabetes mellitus (DM) acarreta abordagem terapêutica e seguimento diferenciados, especialmente em cardiopatas, sendo essencial a prevenção primária e secundária de eventos cardiovasculares nesses pacientes. Objetivos: Observar a presença de DM2 em pacientes cardiopatas portadores de hemoglobina glicada entre 5,7-6,4 %, através da solicitação precoce da curva glicêmica (teste oral de tolerância à glicose - TOTG). Métodos: Foram estudados, de forma retrospectiva, prontuários de 113 pacientes: 51 homens e 62 mulheres, portadores de doença arterial coronariana manifesta ou subclínica, selecionados após avaliação clínica elaboratorial. Foram analisados dosagem de glicemia em jejum, hemoglobina glicada, curva glicêmica, ureia, creatinina, perfil lipídico, idade, sexo, IMC, presença de hipertensão arterial sistêmica, aterosclerose, insuficiência cardíaca, doença arterial coronariana prévia e testes isquêmicos positivos sem necessidade de intervenção. Resultados: Foram diagnosticados como portadores de resistência insulínica através da curva glicêmica 37,2 % dos homens, sendo que 5,9 % apresentavam glicemia de jejum <99mg/dL e 15,7% apresentaram curva compatível do DM2. Quanto à glicemia de 2 horas entre as mulheres, observaram-se 38,8% casos de resistência insulínica, sendo que 19,6 % eram normoglicêmicas na glicemia de jejum e 8 % apresentaram valores >200mg/dL, sendo que 3,2%apresentaram glicemia de jejum <99mg/dL. Conclusão: Pacientes com hemoglobina glicada na faixa para portadores de resistência insulínica eram,na realidade, portadores de DM. Foram identificados pacientes com DM através do TOTG no grupo de portadores de resistência insulínica. A presença de IMC aumentado associou-se à presença de pacientes com DM nesta amostra.


Background: The presence of diabetes mellitus (DM)requires different therapeutic approaches and follow-ups, especially in cardiac patients, with primary and secondary prevention of cardiovascular events being essential for these patients. Objectives: To observe the presence of DM2 in cardiac patients with glycated hemoglobin levels between 5.7 and 6.4% by early requests for glycemic curves obtained through the Oral Glucose ToleranceTest (OGTT). Methods: A retrospective study analyzed the medical records of 113 patients (51 men and 62 women) with manifest or subclinical coronary artery disease, selected after clinical and laboratory evaluation, witht he following measurements: fasting glycemia, glycated hemoglobin, glycemic curve, urea, creatinine, lipids profile, age, gender and BMI, as well as the presence of hypertension, atherosclerosis, heart failure, previous coronary artery disease and positive ischemic tests with no need for intervention. Results: Insulin resistance was diagnosed through glycemic curves in 37.2% of the men, of whom 5.9% had fasting glucose below 99 mg/L and 15.7%presented curves compatible with DM2. Based on glycemia at 2 hours, there were 38.8% cases of insulin resistance among the women, while 19.6% were normoglycemic fasting glucose and 8% had values greater than 200 mg/dL, of which 3.2% had fast ingglucose below 99 mg/dL. Conclusion: Patients with glycated hemoglobin in the insulin resistance range actually had DM, identified through the OGTT in the group with insulin resistance .The presence of increased BMI was associated with the presence of diabetic patients in this sample.


Subject(s)
Humans , Male , Female , Diabetes Mellitus/diagnosis , Cardiovascular Diseases/complications , Glycated Hemoglobin , Insulin Resistance , Cholesterol/blood , Coronary Artery Disease/physiopathology , Retrospective Studies , Sex Factors , Risk , Body Mass Index
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