Cystic fibrosis of pancreas and nephrotic syndrome: a rare association / 소아과

Cystic fibrosis (CF) is a genetic disease with autosomal recessive inheritance and is common in Caucasian people. The prevalence of this disease is between 1/2,000 and 1/3,500 live births, and the incidence varies between populations. Although the CF transmembrane conductance regulator gene is expressed in the kidneys, renal involvement is rare. With advances in the treatment of CF, life expectancy has increased, and some previously unobserved disease associations are now seen in patients with CF. It is important to follow patients with CF for possible abnormalities that may accompany CF. In this paper, we present two rare cases of CF accompanied by nephrotic syndrome.

Paediatric Halitosis and Helicobacter pylori Infection

To compare the presence of Helicobacter pylori [H. pylori] infection by stool antigen test in children with and without halitosis. Comparative study. Department of Paediatrics, Fatih University Hospital, Ankara, Turkey, between December 2008 and June 2009. Fifty-three patients aged between 3-15 years who presented to paediatrics outpatient clinic with halitosis and 55 healthy children aged between 4-15 years without halitosis were included in the study. Halitosis was confirmed with organoleptic test. Stool antigen test was performed in both groups. Intergroup proportions were compared using chi-square and Fisher exact tests with significance at p < 0.05. The H.pylori stool antigen test was positive in 11 out of 53 patients [20.8%] with halitosis and 12 of 55 healthy controls [21.8%]. The rate of positive H. pylori stool antigen test results were similar between two groups [p > 0.05]. Two-weeks eradication treatment was administered to 11 patients with H. pylori infection and halitosis. After treatment, the symptoms of 8 patients with halitosis [72.7%] completely resolved and persisted in 3 patients [27.3%]. Seven of the 11 patients who were administered eradication treatment also had abdominal pain along with halitosis. Both symptoms completely resolved in all those patients after treatment. Although no statistically significant difference existed between the rate of H. pylori infections among those with and without halitosis. Eradication treatment was found beneficial in the treatment of children with halitosis and positive H. pylori stool antigen test