ABSTRACT
Introduction: Thyroid nodules are common. They can beeither benign or malignant. Solitary thyroid nodules have a highlikelihood of being malignant. They should be characterizedproperly for optimum management. Study aimed to find theincidence of malignancy in solitary nodule thyroid.Material and Methods: 54 patients aged between 18 and75 years who underwent solitary thyroid nodules surgeryfrom January 2018 until December 2018 were included.Data collection by meticulous history taking and clinicalexamination, appropriate laboratory and radiologicalinvestigations, operative findings, histopathological report,and follow-up of cases.Results: the Adenomatous colloid goiters were observed in16 patients (30%), followed by Nodular goiter in 10 patients(18.5%). In the present series, papillary carcinoma is thecommonest malignancy of Solitary Thyroid Nodule 8 (80%)of the total of 10 malignancies.Conclusion: Solitary nodule is more common in females.The most common malignancy in solitary nodule thyroid ispapillary carcinoma FNAC is an important investigation in theevaluation of the solitary nodule of thyroid.
ABSTRACT
Cypermethrin (CYP) and Carbendazim (CAR) are synthetic pesticides that have been in use for more than a decade. A study of a low-dose exposure of these pesticides in rat administered different doses of each of these compounds, individually and in combination, followed by investigation of the biochemical and histological status of the rat brain, will highlight early enzymatic and histological changes that generally accompanied a toxic response in the animal. Thus, even though CYP was used at 5, 10, 25 and 50mM, for durations of 12 and 24hr in the different groups of rats, results of the study indicate that simultaneous with changes in enzyme activity, histological sections of specific rat brain yielded observations suggestive of degenerating tissue morphology and architecture even at the low-dose levels.. Tissue specific changes in the activities of these marker enzymes were suggestive of the lack of tissue resistance to pyrethroids or carbamates.