ABSTRACT
The enterically-transmitted hepatitis E virus [HEV] causes large outbreaks and also sporadic cases in various areas of the world. In order to assess the HEV seroprevalence in Tunisia, serum samples from 234 asymptomatic patients have been tested. 3 groups were investigated: group 1 included 100 blood donors, group 2 was made up of 100 individuals aged more than 60 years and the group 3 was composed of 34 children attending paediatric consultation for chronic haematological diseases. The commercial kit ABBOTT HEV EIA was used in this study. The prevalence of HEV infection was respectively 22% in group 1, 46% in group 2 and 29,5% in group 3. This study substantiates the existence of hepatitis E in Tunisia and confirms the increase of its seroprevalence with age. It would be useful to know the means of contamination, which can be achieved by seeking for the virus in water supplies. Besides, more studies are needed to assess the contribution of HEV to acute non A-C hepatitis in Tunisia