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16.
Article in Korean | WPRIM | ID: wpr-61325

ABSTRACT

To evaluate the possible potential of Tc-99m HMPAO SPECT in the differential diagnosis of vertigo, we selected 23 patients and devided them into three groups according to their clinical manifestations: vestibuloneuronitis(VN), benign positional vertigo(BPV), and vertebrobasilar insufficiency (VBI) groups. Then, we prospectively performed SPECT in these patients. In addition, risk factors for strokes, Nylan-Barany tests, brain stem auditory evoked responses(BAER) were investigated. Perfusion defects in the vertebrobasilar territory were evident in 7 out of 8 cases in VBI group, while 1 out of 5, and 2 out of 10 cases showed such findings in BPV and VN groups respectively. We conclude that SPECT may play a role in differential diagnosis of vertigo. It also seems more useful than traditional investigations such as CT, MRI, or BAER in the evaluation of the patients with VBI.


Subject(s)
Humans , Brain Stem , Diagnosis , Diagnosis, Differential , Magnetic Resonance Imaging , Perfusion , Prospective Studies , Risk Factors , Stroke , Technetium Tc 99m Exametazime , Tomography, Emission-Computed, Single-Photon , Vertebrobasilar Insufficiency , Vertigo
17.
Article in English | WPRIM | ID: wpr-138478

ABSTRACT

Automated data processing and quality control of radioimmunoassays offer not only increased speed but also a more thorough and statistically rigorous analysis of results. An external quality assessment scheme for serum thyroxine, triiodothyronine and thyroid stimulating hormone (TSH) assays was performed in five nuclear medicine laboratories in Korea to compare with the assay performances of the World Health Organization Radioimmunoassay Program. The required radioimmunoassay kits were supplied through the International Atomic Energy Agency (IAEA). We have determined the weighted root mean squared error, and variance ratio as the indices of standard curve and also the average batch coefficient of variation (ABCV) as the parameters of response error relationship curve and precision profile. There was a good fit for the triiodothyronine assay, but 3 of 5 laboratories showed possible bad fit in the T4 and TSH assay systems. The ABCV was less than 5 percent for the T3 and T4 assay system, however for the TSH system, only 1 laboratory showed the ABCV value of less than 5 percent. We have also calculated the within batch variation (drift) and between laboratory variations.


Subject(s)
Humans , Electronic Data Processing , Radioimmunoassay/standards , Thyroid Hormones/analysis
18.
Article in English | WPRIM | ID: wpr-138479

ABSTRACT

Automated data processing and quality control of radioimmunoassays offer not only increased speed but also a more thorough and statistically rigorous analysis of results. An external quality assessment scheme for serum thyroxine, triiodothyronine and thyroid stimulating hormone (TSH) assays was performed in five nuclear medicine laboratories in Korea to compare with the assay performances of the World Health Organization Radioimmunoassay Program. The required radioimmunoassay kits were supplied through the International Atomic Energy Agency (IAEA). We have determined the weighted root mean squared error, and variance ratio as the indices of standard curve and also the average batch coefficient of variation (ABCV) as the parameters of response error relationship curve and precision profile. There was a good fit for the triiodothyronine assay, but 3 of 5 laboratories showed possible bad fit in the T4 and TSH assay systems. The ABCV was less than 5 percent for the T3 and T4 assay system, however for the TSH system, only 1 laboratory showed the ABCV value of less than 5 percent. We have also calculated the within batch variation (drift) and between laboratory variations.


Subject(s)
Humans , Electronic Data Processing , Radioimmunoassay/standards , Thyroid Hormones/analysis
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