A Case of Cronkhite-Canada Syndrome with a Remission to Steroid Therapy / 대한소화기내시경학회지

Cronkhite-Canada syndrome is characterized by generalized gastrointestinal polyposis, ectodermal changes, and the eventual development of diarrhea and weight loss. The pathogenesis of the disease is unknown, and there is no established therapy. The disease has a poor prognosis because of malnutrition resulting from altered absorption in the gastrointestinal tract. We experienced a case of a 56-year-old female with Cronkhite-Canada syndrome. After enteral nutrition and administration of prednisolone for 3 months, clinical improvement was noted with cessation of diarrhea, increased serum protein, disappearance of pigmentation, and regrowth of the scalp hair, finger-and toenails. Endoscopy showed resolution of the gastrointestinal polyposis. So we report here a case of diffuse gastrointestinal polyposis which has been in remission with steroid therapy.

Effect of Protein Supplementation by Fish Flour at Weaning Period

Twenty four subjects at weaning period were selected for experimental feeding of 10% fish flour supplements with wheat flour noodles. Experimental regimen was 2 months. Total serum protein, hemoglobin, hematocrit, and red blood cell counts were increased significantly in both sexes. However, a reduction of albumin concentration in serum was found ; also significant increases in globulin fractions occured. Although results suggest an advantage of fish flour supplements, further investigation is required to conclude the definite benefit of fish Hour supplements to Korean children, who need taste acceptability tests of fish flour under strictly controlled conditions.