[New criteria to assess the risk of acute angle closure]

To compare anterior segment and ocular biometric parameters of unaffected fellow eyes of patients with a previous attack of acute angle closure [AAC], primary angle closure suspect [PACS] eyes, and normal eyes; and to assess the risk of developing AAC in PACS. In this prospective comparative observational case series, 16 unaffected fellow eyes of patients with a previous attack of AAC [group I], 40 PACS eyes [group II] and 32 normal eyes [group III] were evaluated. Pentacam and A-scan echography were performed in all cases. Anterior chamber angle [ACA], anterior chamber volume [ACV], anterior chamber depth [ACD], central corneal thickness [CCT], keratometry [KR], lens thickness [LT] and axial length [AL] were measured in all eyes as main outcome measures. Age, CCT and LT were comparable among the study groups [all P values>0.05]. Mean ACA was 24.8, 22.9 and 35.4 in groups I, II, and III respectively [P<0.001]. Corresponding values for ACV were 72, 76 and 172 microl, respectively [P<0.001]. Central ACD measured from the endothelium was 1.80, 1.91, and 3.09 mm in groups I, II, and III respectively [P<0.001]. Using receiver operating characteristic [ROC] curves, ACV

[ case of tuberous sclerosis presenting with eyelid lesions]

To report the clinical, paraclinical and histopathologic features of eyelid mass lesions in a patient with tuberous sclerosis. A 14 year old boy with a slowly progressive right upper lid mass and history of seizures, mental retardation and multiple skin lesions on the face and body was referred to Labbafinejad Medical Center. Cortical tubers and subepandimal nodules were reported in neuroimaging and fibroadenoma with sebaceous hyperplasia were observed on histopathologic assessment. A diagnosis of tuberous sclerosis was made based on multiple major signs and the patient was referred to other subspecialities for comprehensive medical care. The ophthalmologist may be the first specialist to diagnose tuberous sclerosis because of associated ocular signs. Attention to systemic signs is necessary to establish a diagnosis

[Agreement among galilei, orbscan II, and placido disk-based topography]

To evaluate agreement between Galilei, Orbscan II, and placido disk-based topography in terms of keratometry readings, and anterior and posterior elevation. In this prospective comparative study, 184 eyes of 92 keratorefractive surgery candidates were evaluated with Galilei, Orbscan II, and placido disk-based topography. Keratometry readings and anterior and posterior elevation maps were compared using ANOVA and paired t-test. Mean keratometry reading by Galilei, orbscan II and corneal topography was 44.30 +/- 1.49 D, 44.11 +/- 1.47 D, and 44.60 +/- 1.56 D, respectively. The maximum difference in SimK and astigmatism obtained three devices was less than 0.5 D with respect to the anterior and posterior best fitted sphere, the agreement between the Galilei and orbscan II was 0.96 and 0.95, respectively. Maximum elevation of the anterior central cornea was 9.17 +/- 5.1 m by orbscan II and 3.2 +/- 1.78 m by Galilei. Maximum depression of the posterior central cornea was 33.84 +/- 9.33 mm and 6.81 +/- 3.78 m, respectively. Despite a significant difference in mean keratometry readings, the three devices can be used as the difference in measurements was not clinically significant. However a large amount difference was found between Galilei and orbscan II interms of anterior and posterior maximum elevation values