ABSTRACT
The extracts of Pandanus fascicularis Lam. [Pf] root were screened for hepatoprotective action. Albino rats were administered with carbon tetrachloride [CC14] for inducing liver damage. The effect of the extracts was evaluated by measuring the liver enzyme like SOOT, SOPT and bilirubin in the blood serum. The enzyme levels were compared with normal, toxicant and standard groups. In the extract treated animals, there is significant decrease in liver enzyme level. This observation leads to the conclusion that the Pf root possesses hepatoprotective activity. The hepatoprotective activity of the aqueous extract and ethanolic extract was compared with standard drug Silymarin. Aqueous extract shows promising activity when compared to ethanolic extract
ABSTRACT
The effect of alcoholic extract of Cyperus rotundus Linn. on ethanol induced deranged lipid metabolism was summarized. Administration of 18% ethanol for 28 days induces elevation of cholesterol and triglycerides levels. Also ethanol being toxic to liver enzymes like AST and ALT were altered: Simultaneous administration of alcoholic extract of Cyperus rotundus reduced the elevated triglyceride level though the hepatic enzyme levels and cholesterol level were trot reduced. This observation leads to the conclusion that it possesses triglyceride-lowering effect
ABSTRACT
The effect of ethanolic extract of the root of Asparagus racemosus Willd. [REAR] against ethanol induced lipid peroxidation has been summarised. Administration of ethanol [18%] for 45 days induces lipid peroxidation leading to liver damage. Hence the enzyme levels such AST, ALT and alkaline phosphatase which are good markers of liver condition have been elevated and also the triglycerides and cholesterol. Simultaneous administration of REAR at the dose of 165 mg/kg reduced these elevated parameters substantiating that REAR is inhibiting the ethanol induced liver damage in rats