ABSTRACT
Background: spinal Anesthesia has numerous indications in lower abdomen surgery, but duration of analgesia and anesthesia is one of the limitations of this method. Lidocaine-the most common drug in Spinal anesthesia causes a short term anesthesia and analgesia which is lower than one hour. Today different kinds of drugs are for enhancing onset increasing intensity and analgesia duration in spinal anesthesia such as magnesium sulfate which it blocks NMDA receptors
Materials and Methods: in the randomized double blind clinical trial study, 80 patients candidate for first cesarean surgery in Shariati Hospital were divided into two groups. In control group 2ml Lidocaine 5% + 0.5ml sterile water was injected and in the study group 2ml Lidocaine 5% + 0.5ml magnesium sulfate 10% without preservative was injected. The patients were immediately tilted to head up position
Results: level of sensory block was evaluated by pin-prick test in midclavicular line. Analgesia duration was considered from the time of injection until the patient's request for analgesic or complaining of pain. Anesthesia level was T6 in most patients. Analgesic duration in case group was between 160.8+49.1 min, in control group was 113.3+7.3 min. That is statistically significant [p=0.001]
Conclusions: when Mgso4 is added to lidocaine in spinal anesthesia, the duration of analgesia is increased significantly [P<0.05]. This increase of duration of analgesia was not accompanied by increase of side effects. Based on the results of our study, complications such as nausea, vomiting, dyspnea during the surgery and in the recovery room, hypotension during surgery were not statistically different between two groups [p>0.05]