ABSTRACT
Radiofrequency ablation [RFA] and percutaneous ethanol injection [PEI] therapy are currently used for the treatment of hepatocellular carcinoma [HCC]. The objective of this study was to compare the efficacy and safety of combined PEI-RFA versus RFA alone for ablation of HCC. Twenty seven patients with liver cirrhosis and HCC which was 5 - cm in diameter and - 3 in number were enrolled in this study, 12 patients were treated with RFA alone [group I] and 15 patients were treated with PEI-RFA [group II] Post treatment response was assessed by fine needle aspiration biopsy or cytology [FNAB or FNAC] and/or spiral C.T. The overall success rate for tumor ablation in group II was significantly higher [93.75%] than group I [58.33%] [P=0.03] ,with fewer treatment sessions [only 11.7% in group II needed more than one treatment session compared to 58.3%. in group I]. No mortalities or major complications were reported with any of the techniques used. During the follow up period local recurrence occurred in two lesions in two patients in group I [16.67%] versus no reported cases in group II, 58.33% in group I need to do other ablative modalities versus 13.35 in group II [P=0.01]. In conclusion; PEI-RFA is a safe, practical, and effective modality with fewer treatment sessions for the treatment of HCC than RFA alone
ABSTRACT
A village in the Nile delta surveyed for sci istosmiasis by J.A. Scott in 1935 was surveyed again in 1979. The same number of people as in the 1935 survey were randomly selected for investigation by the same parasitological techniques as those used by Scott. The prevalence of Schistosoma mansoni infection had increased from 3.2% to 73%, whereas S.haematobium infection, which had been very common in 1935 [74%], had almost disappeared [2.2%].in the local district hospital since 1972 the percentage of urine specimens found to contain S. haematobium ova has dropped from 30 to 9%, while the percentage of stool specimens containing S.mansoni ova has increased from 2 to 22%. In the local irrigation canals snail intermediate hosts for S.mansoni have outnumbered those for S.haematobium by a factor of 5-40 in the past 7 years. Changes in the proportions of snail vectors appear to be related to construction of the Aswan High Dam and to changes in the water - flow patterns of the Nile. The change in the relative frequencies of the two infections has important public - health implications, since the hepatosplenic schistosorniasis caused by S.mansoni is more difficult to treat and is associated with more morbidity and mortality than the urinary schistosmiasis caused by S.haematobium
ABSTRACT
Thirty patients with portal hypertensive gastropathy and 20 controls were subjected to history and clinical examination, upper G.I. endoscopy and taking antral and body biopsies from the stomach, pathological examination of specimens for histology and H. pylori. The results indicated that H. pylori prevalence was significantly higher in patients with portal hypertensive gastropathy than in the control group. H. pylori was significantly more prevalent in age below five years than above five years. There was no significant relation between prevalence of H. pylori and different grades of varices, hematemesis, melena or previous endoscopy. However, more prevalence was observed in cases having moderate and severe gastropathy. H. pylori was observed in cases having moderate and severe gastropathy. H. pylori was more prevalent in patients with recurrent abdominal pain and/or diarrhea than those without pain or diarrhea