ABSTRACT
Introduction: Polyuria and nocturia may be the first clinical manifestation of hyperthyroidism. Most of the reported studies about renal function in Hyperthyroidism are performed in animals
Material and Methods: In this study we have evaluated 12-hour urine volume and specific gravity of morning urine in 50 new hyperthyroid patients and we have compared the results with similar study in 34 normal persons from their families in the same age group [control]
Results: We found significant increase in urine volume [p<0.001] and decrease in specific gravity in patients with hyperthyroidism [p<0.001]. There was no significant correlation between urine volume and specific gravity with plasma concentration of thyroid hormones
Conclusion: There is increased urine volume and decreased specific gravity. This should be considered in differential diagnosis of diabetes insidious