ABSTRACT
Diabetes mellitus is one of the most common diseases in general population. Its prevalence is 5-8 percent in Iran. The disease has symptoms such as neuropathy. The prevalence of neuropathy is equivalent to 7 percent at onset of the disease, but as the underlying disease advances the prevalence of neuropathy can reach to as much as 50 percent. In some patients with neuropathy, the neuropathic pain can affect their daily functioning and quality of life. The subjects of this clinical trial were 60 patients with type 2 diabetes mellitus who referred to diabetes clinic of Ahvaz Golestan hospital. After proving painful neuropathy, and according to their history, physical examination and EMG-NCV, and considering their inclusion and exclusion criteria for the study, they were randomly divided into two equal groups. The study was accomplished in a double blind method. One group was treated with amitriptyline [50 mg / d] and the other group was treated with carbamazepine [200mg TID]. Based on brief pain inventory quantitative scale amount of pain was scored before and six weeks after the beginning of study. Both drugs were found effective, but no significant difference in pain relief was noted. Hb A1C in patients who received carbamazepine was found lower in comparison with other group. If the glucose declining effect of carbamazepine would be proved in the future, it can be administered as an adjunct therapy
ABSTRACT
Epilepsy can causes some problems for epileptic child and adolescences that are negative effect on quality of life in these patients. relaxation was effective in reducing seizure frequency. Purpose of this study was to investigate the effects of progressive muscular relaxation on quality of life in adolescents with epilepsy. This investigation is a quasi-experimental study. Twenty epileptic people were selected by goal-based sampling. Data were collected in start of research, 4 weeks late and past of intervention by interview, demographic questionnaire and Iranian version of the QOLIE-AD-48 questionnaire. Participants were asked to practice the technique 20 minutes daily at home for 4 weeks. findings had showed school performance had the highest score in quality of life [89.52] and attitude toward epilepsy had the least score in quality of life mean scores [22.5] of patients. Quality of life mean scores improved from 62.27 to 71.95 after intervention period [P<0.001]. All five domains of quality of life scores [epilepsy impact, memory- concentration, health perception, school performance and physical function] [P<0.001] enhanced after relaxation practice period but it was not significant for the mean scores of social support, stigma and attitude toward epilepsy. Findings showed effects of progressive muscular relaxation on improving quality of life of epileptic adolescents
Subject(s)
Humans , Adolescent , Relaxation , Muscle Relaxation , Epilepsy/therapy , Surveys and QuestionnairesABSTRACT
Regarding to the point that CVA is one of major reasons of mortality in aged people; and various studies about role of CRP in the disease prognosis has been done, in the study we have tried to analyze relation ship between CRP Level during bedridden period and disability rate of patient after a month. The research has been gained via studying on 50 patients [27 men.23 women], which by ischemic Cerebral attack in middle cerebral artery pathway [upper branch] regarding to description, clinical examination and cerebral C.T. Scan of Patient have been confirmed to bed. Age average of the patients is 60-80 years old, which regarding to biochemical test of blood at the time of referral to hospital has been divided into two groups: positive CRP [Ml, infectious and inflammatory disease must be rule out] and negative CRP. At the time of bedridden motor function examination, has been recorded in emergency; and after a month. Motor function of patients has been recorded again, [by referring to their homes]. It is clear that both groups had a same treatment care during one month. Muscular force in CVA patients, before treatment, which had positive CRP in comparison with Muscle force patients before treatment with negative CRP had no meaningful difference [P<0.765]. Muscular force had no meaningful difference a month after treatment in patients with positive CRP in comparison with negative CRP [P<0.262], but changes of muscular force before treatment and a month after treatment was meaningful in patients with positive CRP [P<0.014], and muscular force improvement of negative CRP patients was more obvious. Regarding to the point that in the above research it is cleared those CVA patients. Who had positive CRP in comparison with the patients who had negative CRP, had worse prognosis, and so it seems that role of inflammatory elements in prognosis of CVA patients is considerable and analyzable. It is clear that by Considering CRP factor, we may get new treatment strategies