ABSTRACT
Background and Objective: Resistance of Staphylococcus aureus to antibiotics is one of the major global health problems in human societies. Thus, evaluation of pattern of antibiotic resistance in its different strains is very important. This study was carried out to evaluate the antibiotic resistance in Staphylococcus aureus isolated from clinical samples by disk diffusion and PCR methods
Methods: In this laboratory- descriptive study, 50 isolates of Staphylococcus aureus to be identified from clinical specimens. Methicillin resistance was examined using PCR and antibiotic susceptibility of isolates was tested by disk diffusion method
Results: 50 isolates were resistant to methicillin, ampicillin and penicillin. The resistance of isolates to erythromycin, Gentamicin, Clindamycin and Ciprofloxacin were 48%, 34%, 34%, 34%, respectively. The PCR method showed that 98% of Methicillin Resistance of Staphylococcus aureus isolates carried the methicillin resistant gene
Conclusion: This study indicated that 98% isolates harbor mecA genes and more resistant to methicillin related mecA genes
ABSTRACT
Postpartum thyroiditis [PPT] is an autoimmune disease that usually occurs in the first year after parturition and presents with periods of transient thyrotoxicosis and/or hypothyroidism, and in some cases results in permanent hypothyridism. To determine the prevalence of PPT in healthy postpartum women in Shiraz, southern Iran. Of 460 postpartum women from Shiraz 385 cases who had no history of any medical problem or signs of other autoimmune disorders were selected during 1-8 months of postpartum period, to fill a questionnaire about signs and symptoms of their possible thyroid dysfunction. TSH and Anti-Tpo Ab were measured and FT4 assay was done on samples with abnormal TSH. 100 women at reproductive age were randomly selected as control group. Result: The clinical and biochemical prevalence of PPT were 33% and 11.4%, respectively [p<0.01]. Hyperthyroidism was more frequent in early months of postpartum period and hypothyroidism was more frequent in later months. Thyrotoxicosis and hypothyroidism occurred in 34 [8.8%] and 10 [2.6%] mothers, respectively. Positive Anti-Tpo Ab was found in 80% of patients and in 38% of the control group [p<0.0001]. Our results showed a high prevalence of PPT in women in Shiraz. This may be due to the transition from low to adequate iodine intake and participation of women in earlier postpartum period. The major difference compared to other studies is the high frequency of thyrotoxicosis