ABSTRACT
To evaluate the effect of trans-scleral cyclophotocoagulation [TSCPC] in reducing intraocular pressure in eyes with history of pars plana vitrectomy with or without intraocular silicone oil and refractory to medical treatment. Medical records of 35 eyes of 35 patients who underwent TSCPC for medically uncontrolled glaucoma after pars plana vitrectomy for retinal pathology were reviewed retrospectively. Diode laser contact TSCPC was performed at a power of 1-3 watt, for a duration of 2 seconds and with 15-30 applications. Intraocular pressure, visual acuity, number of previous operations, number of medications, number of treatment sessions per eye. Laser parameters and complications were evaluated. After a mean follow-up period of 13.31 +/- 4 [range 6-60] months, mean IOP was decreased from 33.46 +/- 9.80 [12-38] mmHg before surgery to 16.57 +/- 8.21 [2-46] mmHg after TSCPC [P<0.001]. The number of anti-glaucoma medications was reduced from 2.60 +/- 1.09 preoperatively to 1.31 +/- 0.99 at final follow up [P<0.001]. Qualified success and complete success were achieved in 29 [83%] and 9 eyes [20%], respectively. Patients with medically uncontrolled intraocular pressure following to pars plana vitrectomy with or without intravitreal silicone oil can be treated successfully with TSCPC
ABSTRACT
To investigate central corneal thickness [CCT], endothelial cell characteristics and intraocular pressure [IOP] in congenital cataract extracted eyes and to compare the results with eyes of normal age and sex matched controls. CCT and IOP measurements and specular microscopy were performed in 31 eyes of 17 cases of extracted congenital cataracts and 40 eyes of 20 age and sex matched subjects as control group. Mean of three pachymetry measurements of the central cornea was taken as CCT. IOP was measured using an applanation tonometer. Mean CCT was 632 +/- 45 microm in cataract extracted eyes vs 546 +/- 33 microm in the control eyes [P<0.001, independent t test and Mann Whitney test]. There was no significant difference in cell count, coefficient of variation, and mean cell area of the corneal endothelial cells between the two groups. Mean IOP was 22.1 +/- 3.9 mmHg in the cataract extracted eyes and 14.0 +/- 1.6 mmHg in the control group [P<0.001, independent t test]. Although the cornea was clinically clear and there was no significant difference in endothelial characteristics of congenital cataract extracted eyes compared to normal controls, central corneal thickness in operated eyes was significantly greater than that of controls. To differentiate actual glaucoma from artifactual IOP increase, CCT measurement should strongly be considered in these patients
ABSTRACT
To evaluate intermediate-term results of Baerveldt tube implantation for treatment of refractory glaucoma in young patients. We retrospectively studied 14 eyes of 11 consecutive patients aged<20 years with refractory glaucoma who underwent Baerveldt tube implantation after 1 to 3 previous surgical procedures. The glaucoma was congenital in eight eyes and following congenital cataract surgery in four eyes, deep vitrectomy in one eye and post-traumatic in one eye. This study included seven male and four female subjects with mean age of 8.6 +/- 6.3 [range 2-20] years. Mean follow up period was 38 +/- 0.9 months [range 1-4 years]. Mean intraocular pressure [IOP] was 35 +/- 11 mmHg preoperatively which decreased to 16.5 +/- 4.7 mmHg postoperatively [P=0.001]. IOP of 5 to 21 mmHg was achieved in six eyes [42.9%] without antiglaucoma medication and in 12 eyes [85.7%] with or without medication. No loss of light perception or phthisis bulbi occurred during the follow up period. Postoperative interventions included shortening of the tube in one eye [7%], iridectomy at the site of tube due to occlusion by iris in one eye and lens aspiration+PCIOL two years after tube implantation in one eye. Our results show that Baerveldt tube implantation is an effective and safe method for IOP control in young patients with refractory glaucoma
ABSTRACT
To measure peripapillary retinal nerve fiber layer [RNFL] thickness in normal human eyes by optical coherence tomography [OCT].Eighty-one eyes of 45 normal participants were studied. Each person underwent a complete ophthalmic examinations, including measurement of visual aquity and intraocular pressure and evaluation of the anterior segment, optic disc, and retinal nerve fiber layer. None of the participants had any evidence of ocular hypertension [IOP > 21 mmHg], glaucoma or other ocular diseases. Three to six peripapapillary circular scans with a diameter of 3.4 mm were performed on both eyes of participants by optical coherence tomography [model 2000, Carl-Zeiss Med Tec].Subjects ranged in age from 18 to 52 years and refractive error ranged from -5.00 to +1.75 diopters. Average peripapillary RNFL thickness 1.74 mm from the center of the disc was 137.56 +/- 16.79 p.m. Average RNFL thickness in the four quadrants were: superior 161.67 +/- 21.17 p.m, nasal 118.38 +/- 21.97 pm, inferior 163.67 +/- 29.93 pm, and temporal 109.23 +/- 26.35 pm. There were no statistically significant correlation between RNFL thickness and age, gender or refractive error. RNFL thickness in right and left eyes had significant correlation, especially in the inferior quadrant. [r=0.67, P=-0.000].RNFL thickness of both eyes of each person are nearly the same