ABSTRACT
The aim of this study was to design a culturally adapted questionnaire for studying quality of life [QOL] among type 1 and 2 adult diabetes patients in the Islamic Republic of Iran. The 41 items on the questionnaire were based on qualitative research and covered general and health-related QOL. In a descriptive survey, 104 patients completed the questionnaire; 68 [65.4%] were female. Mean age was 50.5 years [standard deviation 12.8]. Most patients [86.5%] had type 2 diabetes. Cronbach's alpha coefficient for the questionnaire was 0.98. The questionnaire successfully distinguished the lower QOL of patients suffering from pain in the limbs, loss of appetite, fatigue, constipation and itching. The questionnaire could determine both general and health-related QOL