ABSTRACT
Background: ribes biebersteinii [Rb] is one of pharmaceutical plants which was used in traditional medicine for decreasing blood sugar
Objective: in this study, effect of aqueous fruit extract of Rb on blood sugar of rats was Investigated
Methods: in this research 60 male Wistar rats were categorized randomly in 10 equal groups with two timeframes [7 and 14 days]. Extraction of Rb was performed with 50 g in 500 ml of distilled water for 18 hours by using a soxhlet extractor. For inducing diabetes, streptozotocin 7 mg/0.5 ml in normal saline was injected intramuscularly per 100 gram of rat body weight. Aqueous fruit extract of Rb was given orally to rats daily [80 mg/0.5 ml in distilled water per 100 gram of rat body weight]. Then the blood samples sent to the laboratory to measure the following factors: glucose, lipids; and activity of the enzymes in plasma serum
Results: ribes biebersteinii compared to diabetic group had significant effect on blood sugar [P
Conclusion: according to the results concluded that extract of Ribes biebersteinii had effect on the blood sugar of rats and led to decrease blood sugar of rats. Because the fruit is rich in anthocyanins, this effect may be due to the antioxidant effect