The epidemiology and clinical findings in enterovirus infections in Negros Oriental

During the first four years of a long range study of enteroviruses at Silliman University Medical Center, evidence was gained of a high level of endemnicity in Dumaguete City and Negros Oriental. Antibodies were detected in 31-83% of 100 lifelong Dumaguete City residents against each of 15 enterovirus types. Seventy-seven enteroviruses were recovered from 518 stool samples, 57 throat swabs and 24 cerebrospinal fluids from patients with a variety of clinical diseases and from 63 stool samples from well children. Although times of high incidence of enterovirus excretion were recorded in the study population, no epidemics of clinical illness referable to enteroviruses were recognized. Available evidence indicated that enteroviruses did not play a prominent primary etiological role in the cases of sporadic disease seen in the hospital The incidence of enterovirus infection in well children was approximately the same as in sick children. (Summary)

Epidemiology of arbovirus infections in Negros Oriental : I. Clinical features of an epidemic in Amlan

An epidemic of probable chikungunya disease occured in Amlan, Negros Oriental from March to October 1968. Six hundred ninety-eight (698) cases were recorded in a post-epidemic survey conducted between October 14-19, 1968The trial of fever, skin rashes, an arthralgia was the prominent feature of the disease. Fever usually began abruptly and usually lasted 2-5 days, but in some cases persisted intermittently over a one to two week period. The skin rashes were mostly described by respondents as either maculopapular or morbilliform. These rashes frequently appeared during defervescence and lasted 2 to 4 days, but reappeared after apparent clinical recovery in some casesArthralgia and occasionally frank arthritis involving large and small joints usually accompanied the onset of pyrexia. Arthralgia frequently persisted for several weeksOne case from Amlan admitted to the Silliman University Medical Center was presented to call attention to the clinical features of the disease. Initial results of serological tests performed on sera collected from this hospitalized patient and other patients in Amlan suggest that the epidemic was due to ckikungunya virus infection.(Summary)