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1.
Indian J Exp Biol ; 1995 Jun; 33(6): 462-3
Article in English | IMSEAR | ID: sea-57167

ABSTRACT

Chlorpromazine, imipramine and amphetamine at a concentration of 0.66, 1.33 and 13.3 x 10(4) M in vitro inhibited acetyl cholinesterase activity by 16, 23 and 31% respectively in rat brain mitochondria. No change in enzyme activity was induced by these drugs in vivo. There is little cholinergic facilitation through acetylcholinesterase inhibition in the presence of psychoactive drugs.


Subject(s)
Acetylcholinesterase/metabolism , Amphetamine/pharmacology , Animals , Brain/enzymology , Chlorpromazine/pharmacology , Cholinesterase Inhibitors/pharmacology , Imipramine/pharmacology , Lithium Chloride/pharmacology , Male , Mitochondria/drug effects , Parasympatholytics/pharmacology , Psychotropic Drugs/pharmacology , Rats , Rats, Inbred Strains
3.
J Indian Med Assoc ; 1986 Apr; 84(4): 116-8
Article in English | IMSEAR | ID: sea-106092
5.
Indian J Exp Biol ; 1976 Nov; 14(6): 663-5
Article in English | IMSEAR | ID: sea-59437
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