Carcinoma of periampullary region; histopathological study and correlation with prognosis

Periampullary malignancies are aggressive neoplasms with low survival rates. The factors favoring long-term survival for periampullary neoplasm are related to histopathologic features, site, stage, resection margins and lymph node metastases. To study some clinical and histopathological parameters of cancer head of pancreas and periampullary region. Statistical study of the impact of these parameters on the outcome of malignancy in this region. This study was carried out on 144 cases of penampullary cancers. The clinical data including, pathological data are revised. Special stains and immunohistochemistry are used when necessary. The most common malignant tumor of peniampullary region is carcinoma of ampulla of vater, then cancer head pancreas, then bile duct carcinoma and lastly duodenal carcinoma [43.7%, 40%, 10% and 6.3% respectively]. We found that the median survival of periampullary cancer is 15 months. The prognosis of these malignant tumors is related to site [P=0.0054], size of the tumor [P=0.0005], grade [P=0.0000], lymph node metastasis [P=0.0123] and tumor stage [P=0.0084]. Other parameters including age and sex, local extension and cut margins are statistically of no significant effects on the prognosis. Periampullary carcinomas are aggressive neoplasm with short survival. It seems that our locality shows epidemiologic factors that leads to that the age of patients at time of presentation and prognosis differ from literatures

Exposure to mercury vapor and impact on health in the dental profession

In this study, detailed measurements of mercury vapor exposure in dental profession were carried out. The study was conducted on 33 dentists and dental nurses with a control group of 30 physicians and nurses work in the same hospital. The results showed that Hg-vapor concentration at any moment was dependant on the level of work-related activities. The urinary Hg concentration in the exposed group was 7.4 mug/L compared with 2.0 mug/L in the control group. There was a positive correlation between urinary Hg concentrations and Hg levels in air among the exposed group. By regression analysis, hours of practice/week and number of amalgam restoration/week were the most predicators of urinary Hg levels in dentistry. The results confirmed that a good ventilation system, the design of dental laboratories and the improvement of dental office hygiene were essential to keep the amount of inhaled or absorbed Hg-vapor below the threshold limits

Risk factors for accident repeatedness among the workers of the iron and steel factory

This study aimed at identifying the risk factors for accident repeatedness among the workers of Iron and Steel Factory in Helwan. The accident records of 71 workers with repeated accidents and 170 workers with single accident for the years [1983-86] were examined. Age and education were personal risk factors for accident repeatedness. The study revealed that accident repeatedness was significantly related to the recorded reasons of accident however no significant association was found with types of accidents, body location affections and types of spar departments