study on age changes in the cartilages of albino rats using protein S-100 antibody

Postnatal samples of the knee joints of different ages of albino rats were taken and fixed by formalin. Specimens were decalcified and exposed to peroxidase anti-peroxidase immunohistochemical technique using S-100 protein as an antibody. In young ages, the chondrocytes were S-100 negative and in adult ages there was positive immunoreactivity in these cells. The positivity disappeared in the old ages, this means that immunoreaction to S-100 protein is localized to the adult normal chondrocytes of the inner core of the articular cartilages. The ageing changes in the cartilage led to disappearance of this positivity. Further investigation is recommended using antirheumatic drugs to show if this positivity returns to these cells with therapy

Osteoarthrosis in patients with chronic haemodialysis

This work aimed to study the frequency, the clinical and radiological pattern of osteoarthritis in hemodialyzed patients. Also, to find out the correlations between such features and age and determine the predisposing factors of osteoarthritis in such patients. The results showed that 52% of patients had one or more joint symptoms. The most commonly affected joint was the knee followed by the hands. The polyarticular affection was detected frequently than the oligoarticular and monoarticular forms. The classical radiological pattern of osteoarthritis was detected in 40% in the hands, 31.5% in the knees and 5.6% in the sacroiliac joint. The features of osteoarthritis in the hemodialyzed patients had another radiological pattern which differs from the classical one with joint space narrowing, periarticular erosion and less marked osteophytes formation and subchondral sclerosis. Also, the age of patients with osteoarthritis was low [38.2 +/- 7.4 years] in patients with hemodialysis

Local Hydrocortisone injection versus infra-red laser therapy in tennis elbow

This study was carried out on 40 patients suffering from tennis elbow according to the diagnostic features mentioned by Adams [1975], Each patient was submitted to clinical assesment before and after 1 and 3 months of treatment in the form of pain score and joint tenderness, The patients were randomly classified into 4 groups Group I; Placebo-group comprised 9 patients Group II, comprised 9 patients were received local injection of 20 mg of triamicinolone acetonide aqueous suspension every week for 4 weeks. Group III: Comprised 10 cases were received probe type of infra-red [I.R.] laser for a total number of 12 sessions taking place every other day. Group IV: Comprised 13 cases were received combination of probe type of I.R. laser and local injection of triamcinolone acetonide aqueous suspension.Comparing the efficacy of these three methods in treating tennis elbow. It was found that in group I: there was a nonsignificant improvement of pain and tenderness scores after I and 3 months. In group II: a significant improvement in both pain and tenderness scores after 1 month and pain score after 3 months, and a nonsignificant improvement in tenderness score after 3 months. In group III: a significant improvement in both pain and tenderness scores after 1 month, and a nonsignificant improvement in pain and tenderness scores after 3 months.In group IV; a high significant improvement in pain and tenderness scores after 1 month and tenderness score after 3 months, and a signficant improvement in pain score after 3 months

analytical study of 2902 cases of paralytic poliomyelitis over twelve years in Assiut governorate

All patients with acute anterior poliomyelitis presenting to the Assiut University Hospital and Assiut Rehabilitation Center over 12 years, from 1978 to 1989, were examined clinically according to the usual poliomyelitis sheet. This study comprises 2902 patients of whom 60.7% were males and 39.3% were females. Concerning the age of affection by the disease we found that 82.6% of the cases between the age of 6 and 24 months and only 1.4% of the cases receiving more than 3 doses of vaccination. The lower limbs is the most common part to be affected [98.5%] and the most common affected muscles are the knee extensors [91.8%] the hip adductors [82.9%] and the ankle dorsiflexors [80.6%]

Effects of infra red laser on the synovium of mice an experimental study

The knee joint of 15 mice were exposed to daily doses of infra-red laser. Five animals were killed after 10, 20 and 30 days of application with an equal number of age matched controls. Histological examination was carried out on paraffin sections stained with Hx, and E. The number of villar profiles of the synovial membrane in the joint were calculated. The volume and surface densities of the synovial membrane in the joint were calculated using stereological techniques. The vascularization of the synovial membrane was also examined. It was found that laser had an enhancing effect on the number of villar profiles, volume and surface densities of the synovial membrane all over the ages. Also, it had an enhancing effect on the vascularization of the synovial membrane all over the ages. The growth pattern of the synovial membrane was preserved. It was concluded that laser application, in therapeutic doses, did not disturb the structural architecture of the synovial membrane and has an enhancing effect on the growth pattern of the synovial membrane