Bleeding Jejunal Metastases Arising From Primary Alveolar Soft Part Sarcoma Of Thigh

Alveolar soft part sarcoma (ASPS) is a rare tumor (0.5–1% of sarcomas) of unknown etiology with a highly characteristic morphology. It tends to occur more often in the younger age group with a predilection for the female sex. Prognosis is generally poor and it often presents with late metastases. Here, we report the case of a 48-year-old female, who presented to the emergency department with a complaint of giddiness and melena. She was a known case of sarcoma ASPS left thigh with pulmonary secondaries. On evaluation, a bleeding tumor in the upper jejunum was found on upper GI endoscopy. As the patient’s hemodynamics were unstable, she had to be operated without further imaging. Post-operative period was uneventful

Gastrointestinal Mixed Neuroendocrine Carcinoma: Case Reports And Review Of Literature

Mixed adenoneuroendocrine carcinoma (MANEC) is a rare and relatively newer entity and classified into a separate category by the WHO 2010 Classification of Tumors. Accordingly, due to its rarity of diagnosis, further oncologic management is a challenge. They contain an adenocarcinoma part and a neuroendocrine part and are further classified based on grades. We present case series with a histological diagnosis of MANEC, its management, and clinical behavior in the follow-up period. Optimum mode of the management of these tumors is yet to be proposed, as these groups of tumors are highly aggressive and associated with poor prognosis.