ABSTRACT
Alcoholic extract of antidiarrhoeal formulation [ADF] containing Holarrhena antidysentrica, Aegle marmelos and Punica granatum was investigated for antidiarrhoeal activity against barium sulphate induced small intestinal transit and castor oil induced diarrhoea in rats. The control, standard and test groups of experimental animals were administered with distilled water, lomotil and ADF [250 mg and 500 mg/kg] orally. Barium sulphate and castor oil were administered after 15 and 60 min. respectively in each group of first and second experiment. The distance travelled by barium sulphate in small intestine was measured after 15 and 30 min. of barium sulphate administration and diarrhoea was observed every 30 min. for 6 hours after castor oil administration. The study showed that ADF caused significant reduction in the distance travelled by barium sulphate and castor oil induced diarrhoea. Thus ADF may have the potential to reduce the diarrhoea in rats
ABSTRACT
Carotid duplex imaging is now recognized as the best non-invasive screening test for carotid artery stenosis. The evidence for its use as the sole diagnostic imaging modality prior to carotid Endarterectomy is examined. Providing it is carried out by experienced trained operators using validated duplex criteria, carotid duplex imaging is safe, highly sensitive and specific, and superior to angiography at plaque characterization and evaluation of flow disturbance. Cerebral CT and MRI should be performed if symptoms are atypical or if there is an evolved stroke. Angiography is required when duplex imaging is sub optional or equivocal, in the presence of atypical symptoms or uncommon vascular abnormalities. In the majority of patients requiring Endarterectomy for symptomatic high grade ICA stenosis, angiography seldom adds relevant information, clinical assessment and carotid duplex imaging alone can be safely used in preoperative assessment
ABSTRACT
The study was carried out on eight patients with clinical presentation of non-traumatic painful swelling of lower limbs and were examined with high resolution Ultrasound probe of 12 MHz on Logic 700 expert series, with average patients age of about 37 years with H/O of uncontrolled diabetes Mellitus, showed discrepancy of circumference / thickness of Calf muscles compared to the opposite normal lower limb with areas of low echogenicity and one patient showed areas of necrosis / abscesses in muscle planes. All were diagnosed and latter confirmed on biopsy as Diabetic muscle infarctions with superadded inflammation