Anti-atherogenic effect of circylating immune complexes in schistosomal hepatic fibrosis

This study included 29 normal control subjects and 76 SHF patients [33 with portosystemic collaterals, 12 with portosystemic collaterals and atherosclerosis, 18 without collaterals and 13 without collaterals with atherosclerosis]. Precipitation of circulating immune complexes [CICs] by ammonium sulfate at 25% saturation and estimation by nephelometry of CICs fractions; namely, immunoglobulins IgG, IgA, IgM, complement C3, apolipoproteins apoA and apoB were done for each subject. Patients with collaterals showed the highest levels of CICs, the atherosclerotic SHF without collaterals showed the lowest level. A similar pattern was shown for the total contents of IgG, IgA, IgM, apoxe A and B fractions of their CICs. Contrarily was the C3 fraction of the CICs which was generally low in the SHF Groups, except in the atherosclerotic group without collaterals who showed an astonishingly high level explaining the ability of their CICs to elicit immune endothelial injury

Neurogenic theory in inflammatory arthritis: neuromadulation by interferential current therapy

The study included 81 patients with chronic knee arthritis suffering from pain, tenderness, effusion and diminished range of movement, they were divided into Group I: included 70 patients with osteoarthritis and group II: including 11 patients with RA, SLE, AS, traumatic synovitis and palindromic rheumatism. Patients were subjected to clinical, radiological and laboratory assessment then they were subjected to IFC therapy. The results of this study showed that, the response of the patients in both groups was quite arthritis. The disappearance of pain end effusion in those patients may give a support to the neurogenic factors in the inflammatory process