ABSTRACT
The effect of Capparis spinosa [C. spinosa] and Acacia arabica [A. arabica] dry powder as plant molluscicide on some glycolytic and gluconeogenic enzymes on snail tissues was investigated. Lactate dehydrogenase [LDH], pyruvate kinase [PK], hexokinase [HK], phosphofructokinase [PFK], glucose phosphate isomerase [GPI] as important glycolytic enzymes were markedly manipulated by both plants when measured one day and one week post-treatment. On the other hand, glucose-6-phosphatase [G-6-Pase], fructose 1.6 diphosphatase [FDpase], phosphoenolpyruvate carboxykinase [PEPCK] as gluconeogenic enzymes were significantly affected by the molluscicidal plants. In addition, some other parameters as glycogen, glucose, total protein, 5-nucleotidase alpha-hydroxybutyrate dehydrogenase [HBDH] and succinate dehydrogenase [SDH] as Krebs cycle enzyme were tested. The study concluded that LC25 and LC50 concentrations of C. spinosa and A. arabica might render B. alexandrina physiologically unsuitable for S. mansoni infection